Showing entry for Prostate cancer, familial


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD018024
Disease NameProstate cancer, familial
Disease CUI IdC2931456
MeSH Codes C04   C12  
Disease Class NameNeoplasms; Male Urogenital Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00214 BXGT003897 Galectin-8 3964 reviewed Signaling
O14656 BXGT004080 Torsin-1A 1861 reviewed Chaperone
O15297 BXGT004149 Protein phosphatase 1D 8493 reviewed Enzyme
O43521 BXGT004598 Bcl-2-like protein 11 10018 reviewed
O43791 BXGT004626 Speckle-type POZ protein 8405 reviewed
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11308 BXGT007684 Transcriptional regulator ERG 2078 reviewed Transcription factor
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P12830 BXGT007852 Cadherin-1 999 reviewed
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P20936 BXGT008619 Ras GTPase-activating protein 1 5921 reviewed Enzyme modulator
P26012 BXGT009083 Integrin beta-8 3696 reviewed Receptor
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P31213 BXGT009515 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6716 reviewed Enzyme
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P50225 BXGT010781 Sulfotransferase 1A1 6817 reviewed
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P55786 BXGT011125 Puromycin-sensitive aminopeptidase 9520 reviewed Enzyme
P57771 BXGT011219 Regulator of G-protein signaling 8 85397 reviewed Enzyme modulator
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q05823 BXGT012840 2-5A-dependent ribonuclease 6041 reviewed Kinase
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q5SQI0 BXGT015839 Alpha-tubulin N-acetyltransferase 1 79969 reviewed
Q86YC2 BXGT017633 Partner and localizer of BRCA2 79728 reviewed
Q8ND30 BXGT018549 Liprin-beta-2 8495 reviewed
Q8NG31 BXGT018565 Kinetochore scaffold 1 57082 reviewed
Q9NR56 BXGT021179 Muscleblind-like protein 1 4154 reviewed Nucleic acid binding
Q9P2W7 BXGT021306 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 27087 reviewed Enzyme
Q9UBB5 BXGT021649 Methyl-CpG-binding domain protein 2 8932 reviewed Epigenetic regulator
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9Y2K7 BXGT022239 Lysine-specific demethylase 2A 22992 reviewed
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y617 BXGT022314 Phosphoserine aminotransferase 29968 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease