adisease

Showing entry for cocaine use

General Disease Information
BXGD Id	BXGD019017
Disease Name	cocaine use
Disease CUI Id	C3496069
MeSH Codes
Disease Class Name
Semantic Type	Mental or Behavioral Dysfunction
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O43612	BXGT004605	Orexin	3060	reviewed
O75751	BXGT005150	Solute carrier family 22 member 3	6581	reviewed	Transporter
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01275	BXGT005747	Glucagon	2641	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P05108	BXGT006317	Cholesterol side-chain cleavage enzyme, mitochondrial	1583	reviewed
P06276	BXGT006430	Cholinesterase	590	reviewed
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P08913	BXGT006841	Alpha-2A adrenergic receptor	150	reviewed	G-protein coupled receptor
P09172	BXGT006865	Dopamine beta-hydroxylase	1621	reviewed
P13497	BXGT007915	Bone morphogenetic protein 1	649	reviewed
P16220	BXGT008206	Cyclic AMP-responsive element-binding protein 1	1385	reviewed
P16581	BXGT008245	E-selectin	6401	reviewed
P19021	BXGT008449	Peptidyl-glycine alpha-amidating monooxygenase	5066	reviewed	Enzyme
P21397	BXGT008644	Amine oxidase [flavin-containing] A	4128	reviewed
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P30536	BXGT009435	Translocator protein	706	reviewed
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35348	BXGT009814	Alpha-1A adrenergic receptor	148	reviewed	G-protein coupled receptor
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	6323	reviewed	Ion channel
P39086	BXGT010093	Glutamate receptor ionotropic, kainate 1	2897	reviewed	Ion channel
P41143	BXGT010223	Delta-type opioid receptor	4985	reviewed	G-protein coupled receptor
P41145	BXGT010225	Kappa-type opioid receptor	4986	reviewed	G-protein coupled receptor
P42785	BXGT010338	Lysosomal Pro-X carboxypeptidase	5547	reviewed	Enzyme
P43004	BXGT010348	Excitatory amino acid transporter 2	6506	reviewed	Transporter
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P47898	BXGT010594	5-hydroxytryptamine receptor 5A	3361	reviewed	G-protein coupled receptor
P51787	BXGT010889	Potassium voltage-gated channel subfamily KQT member 1	3784	reviewed	Ion channel
Q00535	BXGT012534	Cyclin-dependent-like kinase 5	1020	reviewed	Kinase
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q05901	BXGT012842	Neuronal acetylcholine receptor subunit beta-3	1142	reviewed	Ion channel
Q14416	BXGT013468	Metabotropic glutamate receptor 2	2912	reviewed	G-protein coupled receptor
Q14849	BXGT013510	StAR-related lipid transfer protein 3	10948	reviewed
Q15825	BXGT013603	Neuronal acetylcholine receptor subunit alpha-6	8973	reviewed	Ion channel
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q8NCC3	BXGT018546	Group XV phospholipase A2	23659	reviewed	Enzyme
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	10280	reviewed
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9NR19	BXGT021175	Acetyl-coenzyme A synthetase, cytoplasmic	55902	reviewed	Enzyme
Q9UQL6	BXGT021813	Histone deacetylase 5	10014	reviewed	Epigenetic regulator
Q9UQM7	BXGT021814	Calcium/calmodulin-dependent protein kinase type II subunit alpha	815	reviewed	Kinase
Q9Y233	BXGT022210	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	10846	reviewed
Q9Y2I2	BXGT022236	Netrin-G1	22854	reviewed	Enzyme modulator
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}