Showing entry for DNA-(apurinic or apyrimidinic site) lyase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT000846
Protein NameDNA-(apurinic or apyrimidinic site) lyase
Uniport IdA0MTA1
Geneapex1
Gene Id
DomainExo_endo_phos
Pfam PF03372  
OrganismDanio rerio (Zebrafish) (Brachydanio rerio)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006284 base-excision repair
Biological Process GO:0080111 DNA demethylation
Biological Process GO:0060047 heart contraction
Biological Process GO:0001947 heart looping
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0010628 positive regulation of gene expression
molecular function GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
molecular function GO:0003677 DNA binding
molecular function GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity
molecular function GO:0004519 endonuclease activity
molecular function GO:0046872 metal ion binding
molecular function GO:0004528 phosphodiesterase I activity
molecular function GO:0003723 RNA binding
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005739 mitochondrion
cellular component GO:0016607 nuclear speck
cellular component GO:0005730 nucleolus
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002702 Lead 207.2
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein