Showing entry for Sperm-egg fusion protein Juno


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT001463
Protein NameSperm-egg fusion protein Juno
Uniport IdA6ND01
GeneIZUMO1R
Gene Id390243
DomainFolate_rec
Pfam PF03024  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.12 Drug resistance: Antineoplastic hsa01523 Antifolate resistance
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007155 cell adhesion
Biological Process GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization
Biological Process GO:0007338 single fertilization
Biological Process GO:0035036 sperm-egg recognition
molecular function GO:0038023 signaling receptor activity
molecular function GO:0005102 signaling receptor binding
cellular component GO:0031362 anchored component of external side of plasma membrane
cellular component GO:0005576 extracellular region
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-163125 Post-translational modification: synthesis of GPI-anchored proteins
R-HSA-392499 Metabolism of proteins
R-HSA-597592 Post-translational protein modification
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0027651 BXGD002009 Neoplasms Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
BXGC0018397 beta-1,4-mannan 180.06
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein