Showing entry for Centromere protein X


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT001713
Protein NameCentromere protein X
Uniport IdA8MT69
GeneCENPX
Gene Id201254
DomainCENP-X
Pfam PF09415  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.4 Replication and repair hsa03460 Fanconi anemia pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051301 cell division
Biological Process GO:0034080 CENP-A containing nucleosome assembly
Biological Process GO:0036297 interstrand cross-link repair
Biological Process GO:0051382 kinetochore assembly
Biological Process GO:0031398 positive regulation of protein ubiquitination
Biological Process GO:0031297 replication fork processing
Biological Process GO:0000712 resolution of meiotic recombination intermediates
molecular function GO:0003677 DNA binding
cellular component GO:0000777 condensed chromosome kinetochore
cellular component GO:0071821 FANCM-MHF complex
cellular component GO:0043240 Fanconi anaemia nuclear complex
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1640170 Cell Cycle
R-HSA-606279 Deposition of new CENPA-containing nucleosomes at the centromere
R-HSA-6783310 Fanconi Anemia Pathway
R-HSA-73886 Chromosome Maintenance
R-HSA-73894 DNA Repair
R-HSA-774815 Nucleosome assembly
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005890 BXGD000345 Body Height
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009447 BXGD000613 Common Variable Immunodeficiency Immune System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0015625 BXGD001006 Fanconi Anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0234958 BXGD004702 Muscle degeneration Musculoskeletal Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349632 BXGD007939 Splenic Marginal Zone B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0543697 BXGD009291 Mixed cryoglobulinemia Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C3469521 BXGD018910 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein