protein

Showing entry for Toll-like receptor 7

General Target Information
BXGT Id	BXGT002084
Protein Name	Toll-like receptor 7
Uniport Id	B3Y653
Gene	TLR7
Gene Id	574291
Domain	LRR_5; LRR_8; TIR
Pfam	PF13306 PF13855 PF01582
Organism	Macaca mulatta (Rhesus macaque)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0071260	cellular response to mechanical stimulus
Biological Process	GO:0051607	defense response to virus
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling
Biological Process	GO:0007252	I-kappaB phosphorylation
Biological Process	GO:0006955	immune response
Biological Process	GO:0006954	inflammatory response
Biological Process	GO:0045087	innate immune response
Biological Process	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
Biological Process	GO:0032722	positive regulation of chemokine production
Biological Process	GO:0032727	positive regulation of interferon-alpha production
Biological Process	GO:0032728	positive regulation of interferon-beta production
Biological Process	GO:0032729	positive regulation of interferon-gamma production
Biological Process	GO:0032755	positive regulation of interleukin-6 production
Biological Process	GO:0032757	positive regulation of interleukin-8 production
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling
Biological Process	GO:0001932	regulation of protein phosphorylation
Biological Process	GO:0034154	toll-like receptor 7 signaling pathway
Biological Process	GO:0002224	toll-like receptor signaling pathway
molecular function	GO:0003725	double-stranded RNA binding
molecular function	GO:0038187	pattern recognition receptor activity
molecular function	GO:0003727	single-stranded RNA binding
molecular function	GO:0035197	siRNA binding
molecular function	GO:0004888	transmembrane signaling receptor activity
cellular component	GO:0032009	early phagosome
cellular component	GO:0005783	endoplasmic reticulum
cellular component	GO:0005768	endosome
cellular component	GO:0016021	integral component of membrane
cellular component	GO:0005764	lysosome
cellular component	GO:0005886	plasma membrane
cellular component	GO:0043235	receptor complex

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002586	Calcium		40.08
BXGC0018397	beta-1,4-mannan		180.06
BXGC0048348	Guanosine		283.09

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}