Showing entry for Sulfotransferase family cytosolic 2B member 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT003893
Protein NameSulfotransferase family cytosolic 2B member 1
Uniport IdO00204
GeneSULT2B1
Gene Id6820
DomainSulfotransfer_1
Pfam PF00685  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00140 Steroid hormone biosynthesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process
Biological Process GO:0008203 cholesterol metabolic process
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0045606 positive regulation of epidermal cell differentiation
Biological Process GO:0008202 steroid metabolic process
Biological Process GO:0000103 sulfate assimilation
molecular function GO:0004027 alcohol sulfotransferase activity
molecular function GO:0015485 cholesterol binding
molecular function GO:0003676 nucleic acid binding
molecular function GO:1990239 steroid hormone binding
molecular function GO:0050294 steroid sulfotransferase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0070062 extracellular exosome
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0011175 BXGD000701 Dehydration Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0011606 BXGD000735 Exfoliative dermatitis Skin and Connective Tissue Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013592 BXGD000857 Ectropion Eye Diseases
C0014170 BXGD000902 Endometrial Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0017086 BXGD001091 Gangrene Pathological Conditions, Signs and Symptoms
C0019193 BXGD001299 Hepatitis, Toxic Digestive System Diseases; Chemically-Induced Disorders
C0020678 BXGD001463 Hypotrichosis Skin and Connective Tissue Diseases
C0020757 BXGD001466 Ichthyoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0020758 BXGD001467 Congenital ichthyosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033774 BXGD002419 Pruritus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0041834 BXGD002935 Erythema Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0079154 BXGD003065 Congenital Nonbullous Ichthyosiform Erythroderma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0079583 BXGD003082 Ichthyosiform Erythroderma, Congenital Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0151908 BXGD003502 Dry skin Skin and Connective Tissue Diseases
C0153452 BXGD003647 Malignant neoplasm of gallbladder Digestive System Diseases; Neoplasms
C0235782 BXGD004769 Gallbladder Carcinoma Digestive System Diseases; Neoplasms
C0237849 BXGD004849 Peeling of skin
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262444 BXGD005244 Abnormality of the dentition Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0271441 BXGD006203 Chronic otitis media Otorhinolaryngologic Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0349588 BXGD007933 Short stature
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0853087 BXGD010964 Nail abnormality Pathological Conditions, Signs and Symptoms
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C0870082 BXGD011309 Hyperkeratosis Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C1262760 BXGD011886 Hepatitis, Drug-Induced Digestive System Diseases; Chemically-Induced Disorders
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1837770 BXGD014270 Sparse hair
C1853246 BXGD015323 Eversion of lower lip
C1856660 BXGD015629 Abnormality of the helix
C1963094 BXGD016681 Dry Skin, CTCAE
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2919142 BXGD017867 Short Stature, CTCAE
C3658290 BXGD019256 Drug-Induced Acute Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C3670629 BXGD019327 Orthokeratotic hyperkeratosis
C3806482 BXGD019514 Recurrent respiratory infections Infections; Respiratory Tract Diseases
C3888093 BXGD019949 ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C4021956 BXGD020839 Aplasia/Hypoplasia of the eyebrow
C4021998 BXGD020862 Lack of skin elasticity
C4277682 BXGD022376 Chemical and Drug Induced Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4279912 BXGD022378 Chemically-Induced Liver Toxicity Digestive System Diseases; Chemically-Induced Disorders
C4525297 BXGD023131 Stage 0 Gallbladder Cancer AJCC v8
C4525300 BXGD023132 Stage IIA Gallbladder Cancer AJCC v8
C4525301 BXGD023133 Stage IIB Gallbladder Cancer AJCC v8
C4525302 BXGD023134 Stage III Gallbladder Cancer AJCC v8
C4525305 BXGD023135 Stage IV Gallbladder Cancer AJCC v8
C4539754 BXGD023227 ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 14
C4551630 BXGD023375 Ichthyosis Congenita I Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C4553962 BXGD023553 Hyperkeratosis, CTCAE
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0029355 Pregnenolone 316.24
BXGC0038316 Cholesterol 386.35
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein