Showing entry for Rho-related GTP-binding protein RhoD


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT003895
Protein NameRho-related GTP-binding protein RhoD
Uniport IdO00212
GeneRHOD
Gene Id29984
DomainRas
Pfam PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.8 Development hsa04360 Axon guidance
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0051017 actin filament bundle assembly
Biological Process GO:0007015 actin filament organization
Biological Process GO:0016477 cell migration
Biological Process GO:0030865 cortical cytoskeleton organization
Biological Process GO:0048041 focal adhesion assembly
Biological Process GO:0030032 lamellipodium assembly
Biological Process GO:0045785 positive regulation of cell adhesion
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0006605 protein targeting
Biological Process GO:0032956 regulation of actin cytoskeleton organization
Biological Process GO:2000249 regulation of actin cytoskeleton reorganization
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0051893 regulation of focal adhesion assembly
Biological Process GO:0051056 regulation of small GTPase mediated signal transduction
Biological Process GO:0007266 Rho protein signal transduction
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0019901 protein kinase binding
cellular component GO:0005938 cell cortex
cellular component GO:0042995 cell projection
cellular component GO:0005737 cytoplasm
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0005769 early endosome
cellular component GO:0010008 endosome membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-194315 Signaling by Rho GTPases
R-HSA-194840 Rho GTPase cycle
R-HSA-195258 RHO GTPase Effectors
R-HSA-5663220 RHO GTPases Activate Formins
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003872 BXGD000235 Arthritis, Psoriatic Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007192 BXGD000450 Cardiomyopathy, Alcoholic Chemically-Induced Disorders; Cardiovascular Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0332840 BXGD006900 Amputated structure (morphologic abnormality) Wounds and Injuries
C0339573 BXGD007271 Glaucoma, Primary Open Angle Eye Diseases
C0349530 BXGD007916 Early gastric cancer Digestive System Diseases; Neoplasms
C0489786 BXGD009018 Height
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3544347 BXGD019116 Intestinal fibrosis
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein