Showing entry for Excitatory amino acid transporter 5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT003913
Protein NameExcitatory amino acid transporter 5
Uniport IdO00341
GeneSLC1A7
Gene Id6512
DomainSDF
Pfam PF00375  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.6 Nervous system hsa04721 Synaptic vesicle cycle
5. Organismal Systems 5.6 Nervous system hsa04724 Glutamatergic synapse
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006835 dicarboxylic acid transport
Biological Process GO:0014047 glutamate secretion
Biological Process GO:0006811 ion transport
Biological Process GO:0001504 neurotransmitter uptake
molecular function GO:0005313 L-glutamate transmembrane transporter activity
molecular function GO:0015293 symporter activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-112310 Neurotransmitter release cycle
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-210500 Glutamate Neurotransmitter Release Cycle
R-HSA-382551 Transport of small molecules
R-HSA-425393 Transport of inorganic cations/anions and amino acids/oligopeptides
R-HSA-425407 SLC-mediated transmembrane transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005890 BXGD000345 Body Height
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0023281 BXGD001628 Leishmaniasis Infections; Skin and Connective Tissue Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0202236 BXGD004086 Triglycerides measurement
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1445957 BXGD013081 Serum total cholesterol measurement
C2985280 BXGD018223 Blood Protein Measurement
C4315130 BXGD022694 Hippocampal atrophy
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006162 L-Glutamic acid 147.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein