Showing entry for Synaptotagmin-5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT003922
Protein NameSynaptotagmin-5
Uniport IdO00445
GeneSYT5
Gene Id6861
DomainC2
Pfam PF00168  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0017156 calcium-ion regulated exocytosis
Biological Process GO:0048791 calcium ion-regulated exocytosis of neurotransmitter
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0017158 regulation of calcium ion-dependent exocytosis
Biological Process GO:0014059 regulation of dopamine secretion
Biological Process GO:0048488 synaptic vesicle endocytosis
Biological Process GO:0016079 synaptic vesicle exocytosis
Biological Process GO:0016192 vesicle-mediated transport
molecular function GO:0005544 calcium-dependent phospholipid binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0030276 clathrin binding
molecular function GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
molecular function GO:0001786 phosphatidylserine binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0000149 SNARE binding
molecular function GO:0019905 syntaxin binding
cellular component GO:0030424 axon
cellular component GO:0031045 dense core granule
cellular component GO:0070382 exocytic vesicle
cellular component GO:0099066 integral component of neuronal dense core vesicle membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:1990769 proximal neuron projection
cellular component GO:0055038 recycling endosome membrane
cellular component GO:0030672 synaptic vesicle membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-163685 Integration of energy metabolism
R-HSA-422356 Regulation of insulin secretion
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0003705 Chloride 35.45
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein