Showing entry for Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT003943
Protein NamePhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
Uniport IdO00750
GenePIK3C2B
Gene Id5287
DomainC2; PI3Ka; PI3K_C2; PI3K_rbd; PI3_PI4_kinase; PX
Pfam PF00168   PF00454   PF00792   PF00794   PF00613   PF00787  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00562 Inositol phosphate metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
3. Environmental Information Processing 3.2 Signal transduction hsa04070 Phosphatidylinositol signaling system
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1905037 autophagosome organization
Biological Process GO:0016477 cell migration
Biological Process GO:0009267 cellular response to starvation
Biological Process GO:0014065 phosphatidylinositol 3-kinase signaling
Biological Process GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process
Biological Process GO:0006661 phosphatidylinositol biosynthetic process
Biological Process GO:0048015 phosphatidylinositol-mediated signaling
Biological Process GO:0046854 phosphatidylinositol phosphorylation
Biological Process GO:0043491 protein kinase B signaling
molecular function GO:0016303 1-phosphatidylinositol-3-kinase activity
molecular function GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity
molecular function GO:0005524 ATP binding
molecular function GO:0001727 lipid kinase activity
molecular function GO:0035091 phosphatidylinositol binding
molecular function GO:0052742 phosphatidylinositol kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0030139 endocytic vesicle
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0016020 membrane
cellular component GO:0005654 nucleoplasm
cellular component GO:0005942 phosphatidylinositol 3-kinase complex
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1483255 PI Metabolism
R-HSA-1483257 Phospholipid metabolism
R-HSA-1660499 Synthesis of PIPs at the plasma membrane
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0016529 BXGD001068 Forced expiratory volume function
C0017638 BXGD001132 Glioma Neoplasms
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0042834 BXGD003004 Vital capacity
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0205682 BXGD004105 Waist-Hip Ratio
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C1269955 BXGD012005 Tumor Cell Invasion
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1518922 BXGD013229 peak expiratory flow (procedure)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2698259 BXGD017449 Monoclonal B-Cell Lymphocytosis Neoplasms; Hemic and Lymphatic Diseases
C2938940 BXGD018168 Post stroke depression Mental Disorders
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4509816 BXGD022975 Squamous non-small cell lung cancer Neoplasms; Respiratory Tract Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein