Showing entry for Alpha-1A adrenergic receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT003959
Protein NameAlpha-1A adrenergic receptor
Uniport IdO02824
GeneADRA1A
Gene Id100009237
Domain7tm_1
Pfam PF00001  
OrganismOryctolagus cuniculus (Rabbit)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007512 adult heart development
Biological Process GO:0061049 cell growth involved in cardiac muscle cell development
Biological Process GO:0010507 negative regulation of autophagy
Biological Process GO:0001985 negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure
Biological Process GO:0150099 neuron-glial cell signaling
Biological Process GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0097195 pilomotor reflex
Biological Process GO:0010613 positive regulation of cardiac muscle hypertrophy
Biological Process GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:1903997 positive regulation of non-membrane spanning protein tyrosine kinase activity
Biological Process GO:0045987 positive regulation of smooth muscle contraction
Biological Process GO:0001997 positive regulation of the force of heart contraction by epinephrine-norepinephrine
Biological Process GO:0055117 regulation of cardiac muscle contraction
Biological Process GO:0019229 regulation of vasoconstriction
molecular function GO:0004937 alpha1-adrenergic receptor activity
molecular function GO:0046982 protein heterodimerization activity
cellular component GO:0005901 caveola
cellular component GO:0005737 cytoplasm
cellular component GO:0016021 integral component of membrane
cellular component GO:0031965 nuclear membrane
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0021210 Phenylpropanolamine 151.1
BXGC0027118 Tamsulosin 408.17
BXGC0046755 Yohimbine 354.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein