Showing entry for Estrogen receptor beta


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004028
Protein NameEstrogen receptor beta
Uniport IdO08537
GeneEsr2
Gene Id13983
DomainERbeta_N; Hormone_recep; zf-C4
Pfam PF12497   PF00104   PF00105  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001662 behavioral fear response
Biological Process GO:0007420 brain development
Biological Process GO:0071392 cellular response to estradiol stimulus
Biological Process GO:0060743 epithelial cell maturation involved in prostate gland development
Biological Process GO:0044849 estrous cycle
Biological Process GO:0008628 hormone-mediated apoptotic signaling pathway
Biological Process GO:0030520 intracellular estrogen receptor signaling pathway
Biological Process GO:0030518 intracellular steroid hormone receptor signaling pathway
Biological Process GO:0007611 learning or memory
Biological Process GO:0060766 negative regulation of androgen receptor signaling pathway
Biological Process GO:0048521 negative regulation of behavior
Biological Process GO:0060548 negative regulation of cell death
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0050680 negative regulation of epithelial cell proliferation
Biological Process GO:2000252 negative regulation of feeding behavior
Biological Process GO:1901215 negative regulation of neuron death
Biological Process GO:2000378 negative regulation of reactive oxygen species metabolic process
Biological Process GO:0048662 negative regulation of smooth muscle cell proliferation
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0001764 neuron migration
Biological Process GO:0001541 ovarian follicle development
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0097755 positive regulation of blood vessel diameter
Biological Process GO:0051091 positive regulation of DNA-binding transcription factor activity
Biological Process GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0060740 prostate gland epithelium morphogenesis
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0043523 regulation of neuron apoptotic process
Biological Process GO:0033574 response to testosterone
Biological Process GO:0060011 Sertoli cell proliferation
Biological Process GO:0060065 uterus development
Biological Process GO:0060068 vagina development
molecular function GO:0003677 DNA binding
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0008144 drug binding
molecular function GO:0019899 enzyme binding
molecular function GO:1903924 estradiol binding
molecular function GO:0030284 estrogen receptor activity
molecular function GO:0034056 estrogen response element binding
molecular function GO:0042562 hormone binding
molecular function GO:0042802 identical protein binding
molecular function GO:0004879 nuclear receptor activity
molecular function GO:0042975 peroxisome proliferator activated receptor binding
molecular function GO:1990841 promoter-specific chromatin binding
molecular function GO:0070491 repressing transcription factor binding
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:0005496 steroid binding
molecular function GO:1990239 steroid hormone binding
molecular function GO:0003707 steroid hormone receptor activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005929 cilium
cellular component GO:0005737 cytoplasm
cellular component GO:0005739 mitochondrion
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0005634 nucleus
cellular component GO:0043204 perikaryon
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0032993 protein-DNA complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000130 Estradiol 272.38
BXGC0001325 Progesterone 314.46
BXGC0003707 Estrogen 268.36
BXGC0005989 Auraptene 298.38
BXGC0006362 Estrone 270.37
BXGC0019164 Raloxifene 473.17
BXGC0030094 Paroxypropione 150.07
BXGC0031233 Umbelliprenin 366.22
BXGC0034968 Dienestrol 266.13
BXGC0037591 7-Prenyloxycoumarin 230.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein