protein

Showing entry for Growth/differentiation factor 8

General Target Information
BXGT Id	BXGT004034
Protein Name	Growth/differentiation factor 8
Uniport Id	O08689
Gene	Mstn
Gene Id	17700
Domain	TGFb_propeptide; TGF_beta
Pfam	PF00019 PF00688
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0071549	cellular response to dexamethasone stimulus
Biological Process	GO:0046716	muscle cell cellular homeostasis
Biological Process	GO:0014839	myoblast migration involved in skeletal muscle regeneration
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway
Biological Process	GO:0033673	negative regulation of kinase activity
Biological Process	GO:0014741	negative regulation of muscle hypertrophy
Biological Process	GO:0045662	negative regulation of myoblast differentiation
Biological Process	GO:2000818	negative regulation of myoblast proliferation
Biological Process	GO:0051898	negative regulation of protein kinase B signaling
Biological Process	GO:1902725	negative regulation of satellite cell differentiation
Biological Process	GO:1902723	negative regulation of skeletal muscle satellite cell proliferation
Biological Process	GO:0048632	negative regulation of skeletal muscle tissue growth
Biological Process	GO:0022602	ovulation cycle process
Biological Process	GO:0010592	positive regulation of lamellipodium assembly
Biological Process	GO:0010759	positive regulation of macrophage chemotaxis
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
Biological Process	GO:0045893	positive regulation of transcription, DNA-templated
Biological Process	GO:0051602	response to electrical stimulus
Biological Process	GO:0043627	response to estrogen
Biological Process	GO:0045471	response to ethanol
Biological Process	GO:0009629	response to gravity
Biological Process	GO:0009408	response to heat
Biological Process	GO:0014850	response to muscle activity
Biological Process	GO:0033574	response to testosterone
Biological Process	GO:0014732	skeletal muscle atrophy
Biological Process	GO:0060395	SMAD protein signal transduction
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway
molecular function	GO:0005125	cytokine activity
molecular function	GO:0008083	growth factor activity
molecular function	GO:0008201	heparin binding
molecular function	GO:0042802	identical protein binding
molecular function	GO:0042803	protein homodimerization activity
molecular function	GO:0005102	signaling receptor binding
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005576	extracellular region
cellular component	GO:0005615	extracellular space

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0037687	(4S)-2-methylpentane-2,4-diol		118.1

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}