Showing entry for Disintegrin and metalloproteinase domain-containing protein 10


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004081
Protein NameDisintegrin and metalloproteinase domain-containing protein 10
Uniport IdO14672
GeneADAM10
Gene Id102
DomainDisintegrin; Pep_M12B_propep; Reprolysin_2
Pfam PF00200   PF01562  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.4 Neurodegenerative diseases hsa05010 Alzheimer disease
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034332 adherens junction organization
Biological Process GO:0034205 amyloid-beta formation
Biological Process GO:0042987 amyloid precursor protein catabolic process
Biological Process GO:0007267 cell-cell signaling
Biological Process GO:0044267 cellular protein metabolic process
Biological Process GO:0090102 cochlea development
Biological Process GO:0051089 constitutive protein ectodomain proteolysis
Biological Process GO:0022617 extracellular matrix disassembly
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0006509 membrane protein ectodomain proteolysis
Biological Process GO:0042117 monocyte activation
Biological Process GO:0007162 negative regulation of cell adhesion
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0035333 Notch receptor processing, ligand-dependent
Biological Process GO:0007219 Notch signaling pathway
Biological Process GO:0051088 PMA-inducible membrane protein ectodomain proteolysis
Biological Process GO:0046931 pore complex assembly
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0030307 positive regulation of cell growth
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0010820 positive regulation of T cell chemotaxis
Biological Process GO:0099173 postsynapse organization
Biological Process GO:0043687 post-translational protein modification
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0016485 protein processing
Biological Process GO:0061001 regulation of dendritic spine morphogenesis
Biological Process GO:0098696 regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
Biological Process GO:0008593 regulation of Notch signaling pathway
Biological Process GO:1901342 regulation of vasculature development
Biological Process GO:0097327 response to antineoplastic agent
Biological Process GO:0034612 response to tumor necrosis factor
Biological Process GO:0007283 spermatogenesis
Biological Process GO:1901998 toxin transport
molecular function GO:0004175 endopeptidase activity
molecular function GO:0005178 integrin binding
molecular function GO:0046872 metal ion binding
molecular function GO:0004222 metalloendopeptidase activity
molecular function GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process
molecular function GO:0008237 metallopeptidase activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0017124 SH3 domain binding
molecular function GO:0005102 signaling receptor binding
cellular component GO:0005912 adherens junction
cellular component GO:0030424 axon
cellular component GO:0009986 cell surface
cellular component GO:0030136 clathrin-coated vesicle
cellular component GO:0005737 cytoplasm
cellular component GO:0043197 dendritic spine
cellular component GO:0005788 endoplasmic reticulum lumen
cellular component GO:0070062 extracellular exosome
cellular component GO:0005925 focal adhesion
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005798 Golgi-associated vesicle
cellular component GO:0000139 Golgi membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0005634 nucleus
cellular component GO:0097038 perinuclear endoplasmic reticulum
cellular component GO:0005886 plasma membrane
cellular component GO:0046930 pore complex
cellular component GO:0014069 postsynaptic density
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0035579 specific granule membrane
cellular component GO:0097060 synaptic membrane
cellular component GO:0008021 synaptic vesicle
cellular component GO:0070821 tertiary granule membrane
cellular component GO:0097197 tetraspanin-enriched microdomain
cellular component GO:0005802 trans-Golgi network
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-1442490 Collagen degradation
R-HSA-1474228 Degradation of the extracellular matrix
R-HSA-1474228 Degradation of the extracellular matrix
R-HSA-1474244 Extracellular matrix organization
R-HSA-1474244 Extracellular matrix organization
R-HSA-157118 Signaling by NOTCH
R-HSA-157118 Signaling by NOTCH
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-177929 Signaling by EGFR
R-HSA-1980143 Signaling by NOTCH1
R-HSA-1980145 Signaling by NOTCH2
R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus
R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer
R-HSA-2644603 Signaling by NOTCH1 in Cancer
R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants
R-HSA-2660825 Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
R-HSA-2660826 Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
R-HSA-2682334 EPH-Ephrin signaling
R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer
R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants
R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus
R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-HSA-392499 Metabolism of proteins
R-HSA-3928665 EPH-ephrin mediated repulsion of cells
R-HSA-422475 Axon guidance
R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers
R-HSA-597592 Post-translational protein modification
R-HSA-6798695 Neutrophil degranulation
R-HSA-8957275 Post-translational protein phosphorylation
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-9012852 Signaling by NOTCH3
R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus
R-HSA-9013694 Signaling by NOTCH4
R-HSA-9013700 NOTCH4 Activation and Transmission of Signal to the Nucleus
R-HSA-9675108 Nervous system development
R-HSA-977225 Amyloid fiber formation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002452 BXGD000116 Amelogenesis Imperfecta Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0002792 BXGD000129 anaphylaxis Immune System Diseases
C0002962 BXGD000160 Angina Pectoris Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006111 BXGD000369 Brain Diseases Nervous System Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0006840 BXGD000409 Candidiasis Infections
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007129 BXGD000439 Merkel cell carcinoma Neoplasms; Infections
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008073 BXGD000518 Developmental Disabilities Mental Disorders
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010606 BXGD000677 Adenoid Cystic Carcinoma Neoplasms
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014511 BXGD000920 Epithelial cyst Neoplasms
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0016667 BXGD001072 Fragile X Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017658 BXGD001138 Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0021933 BXGD001524 Intussusception Digestive System Diseases
C0022336 BXGD001535 Creutzfeldt-Jakob disease Infections; Nervous System Diseases; Mental Disorders
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024314 BXGD001767 Lymphoproliferative Disorders Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025500 BXGD001874 Mesothelioma Neoplasms
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027430 BXGD001988 Nasal Polyps Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029531 BXGD002164 Other cataract Eye Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0030805 BXGD002256 Bullous pemphigoid Skin and Connective Tissue Diseases; Immune System Diseases
C0030809 BXGD002258 Pemphigus Vulgaris Skin and Connective Tissue Diseases; Immune System Diseases
C0031036 BXGD002273 Polyarteritis Nodosa Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0033141 BXGD002400 Cardiomyopathies, Primary Cardiovascular Diseases
C0033575 BXGD002407 Prostatic Diseases Male Urogenital Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036457 BXGD002617 Scrapie Infections; Nervous System Diseases; Animal Diseases
C0036529 BXGD002624 Myocardial Diseases, Secondary Cardiovascular Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037278 BXGD002678 Skin Diseases, Infectious Infections; Skin and Connective Tissue Diseases
C0038160 BXGD002734 Staphylococcal Infections Infections
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0040021 BXGD002834 Thromboangiitis Obliterans Cardiovascular Diseases
C0040188 BXGD002850 Tic disorder Nervous System Diseases; Mental Disorders
C0041956 BXGD002942 Ureteral obstruction Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042842 BXGD003005 Vitamin A Deficiency Nutritional and Metabolic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085220 BXGD003142 Cerebral Amyloid Angiopathy Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases
C0085413 BXGD003171 Polycystic Kidney, Autosomal Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0085650 BXGD003223 Purpura Fulminans Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0149521 BXGD003328 Pancreatitis, Chronic Digestive System Diseases
C0149654 BXGD003343 Conduct Disorder Mental Disorders
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151718 BXGD003464 Hypocholesterolemia Nutritional and Metabolic Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0162534 BXGD003953 Prion Diseases Infections; Nervous System Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0162872 BXGD003997 Aortic Aneurysm, Thoracic Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206019 BXGD004144 HIV Encephalopathy Infections; Immune System Diseases; Nervous System Diseases; Mental Disorders
C0206702 BXGD004252 Klatskin Tumor Neoplasms
C0220597 BXGD004292 Adult Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0220644 BXGD004306 Childhood Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0234985 BXGD004708 Mental deterioration Mental Disorders
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242584 BXGD005179 Autoimmune thrombocytopenia Immune System Diseases; Hemic and Lymphatic Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0264270 BXGD005377 Hypertrophic rhinitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0264732 BXGD005421 Cardiac dilatation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0272286 BXGD006337 Thrombocytopenia due to platelet alloimmunization Hemic and Lymphatic Diseases
C0276496 BXGD006426 Familial Alzheimer Disease (FAD) Nervous System Diseases; Mental Disorders
C0276548 BXGD006430 HIV encephalitis Infections; Immune System Diseases; Nervous System Diseases; Mental Disorders
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280321 BXGD006739 Squamous cell carcinoma of the hypopharynx
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333463 BXGD006954 Senile Plaques Pathological Conditions, Signs and Symptoms
C0334634 BXGD007144 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349566 BXGD007928 Squamous cell carcinoma of tongue Neoplasms; Stomatognathic Diseases
C0376286 BXGD007984 Avitaminosis Nutritional and Metabolic Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0398650 BXGD008212 Immune thrombocytopenic purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases
C0406811 BXGD008375 Reticulate acropigmentation of Kitamura Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0523465 BXGD009209 Serum albumin measurement
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0546126 BXGD009328 Acute Confusional Senile Dementia Nervous System Diseases; Mental Disorders
C0595989 BXGD009632 Carcinoma of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0750900 BXGD010241 Alzheimer's Disease, Focal Onset Nervous System Diseases; Mental Disorders
C0750901 BXGD010242 Alzheimer Disease, Early Onset Nervous System Diseases; Mental Disorders
C0796149 BXGD010804 Scott Syndrome Hemic and Lymphatic Diseases
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0850666 BXGD010901 Infection caused by Helicobacter pylori Infections
C0856169 BXGD011096 Endothelial dysfunction
C0870082 BXGD011309 Hyperkeratosis Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0876973 BXGD011322 Infectious Lung Disorder Infections; Respiratory Tract Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0947751 BXGD011494 Vascular inflammations Cardiovascular Diseases
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C0948588 BXGD011542 Lymphangiosis carcinomatosa Hemic and Lymphatic Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1270972 BXGD012006 Mild cognitive disorder Mental Disorders
C1275122 BXGD012060 Familial multiple trichoepitheliomata Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1318485 BXGD012394 Liver regeneration disorder Digestive System Diseases
C1321872 BXGD012446 Stage IV Skin Melanoma Neoplasms; Skin and Connective Tissue Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510471 BXGD013169 Vitamin Deficiency Nutritional and Metabolic Diseases
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1519680 BXGD013244 Tumor Immunity Pathological Conditions, Signs and Symptoms
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1719672 BXGD013659 Severe Sepsis Pathological Conditions, Signs and Symptoms; Infections
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1843013 BXGD014549 Alzheimer disease, familial, type 3 Nervous System Diseases; Mental Disorders
C1955760 BXGD016608 Idiopathic normal pressure hydrocephalus (INPH)
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1960398 BXGD016658 HER2-positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C2936349 BXGD018109 Plaque, Amyloid Pathological Conditions, Signs and Symptoms
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3714534 BXGD019411 dowling-degos disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C3810041 BXGD019631 ALZHEIMER DISEASE 18
C3887654 BXGD019912 POLYARTERITIS NODOSA, CHILDHOOD-ONSET Skin and Connective Tissue Diseases; Cardiovascular Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4552092 BXGD023486 Dowling-Degos disease 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C4553962 BXGD023553 Hyperkeratosis, CTCAE
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4721414 BXGD023738 Mantle cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0021255 4-[(3S)-8,8-Dimethyl-3,4-Dihydro-2H-Pyrano[2,3-F]Chromen-3-Yl]Benzene-1,3-Diol 324.14
BXGC0022009 (9R)-9-[(9R)-2-Carboxy-4-Hydroxy-10-Oxo-5-[(3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-9H-Anthracen-9-Yl]-4-Hydroxy-10-Oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-9H-Anthracene-2-Carboxylic Acid 862.2
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein