Showing entry for Regulator of G-protein signaling 12


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004111
Protein NameRegulator of G-protein signaling 12
Uniport IdO14924
GeneRGS12
Gene Id6002
DomainGoLoco; PDZ; RBD; RGS; RGS12_us1; RGS12_us2; RGS12_usC
Pfam PF02188   PF00595   PF02196   PF00615  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0009968 negative regulation of signal transduction
Biological Process GO:0008277 regulation of G protein-coupled receptor signaling pathway
molecular function GO:0005096 GTPase activator activity
molecular function GO:0003924 GTPase activity
molecular function GO:0030695 GTPase regulator activity
cellular component GO:0000794 condensed nuclear chromosome
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0016363 nuclear matrix
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-418594 G alpha (i) signalling events
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0005890 BXGD000345 Body Height
C0005940 BXGD000352 Bone Diseases Musculoskeletal Diseases
C0013264 BXGD000808 Muscular Dystrophy, Duchenne Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0017654 BXGD001136 Glomerular Filtration Rate
C0018021 BXGD001162 Goiter Endocrine System Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0032181 BXGD002332 Platelet Count measurement
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0041296 BXGD002903 Tuberculosis Infections
C0201976 BXGD004063 Creatinine measurement, serum (procedure)
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0234958 BXGD004702 Muscle degeneration Musculoskeletal Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0410158 BXGD008408 Muscle damage
C0523465 BXGD009209 Serum albumin measurement
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C1305855 BXGD012348 Body mass index
C1445957 BXGD013081 Serum total cholesterol measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000099 3,4-Dihydroxyphenylacetic acid 168.15
BXGC0000194 Sanguinarine 332.33
BXGC0001091 Allantoin 158.12
BXGC0002071 Apigenin 270.24
BXGC0005985 Piceatannol 244.25
BXGC0006306 Myricetin 318.24
BXGC0018772 Pseudoephedrine 165.12
BXGC0044857 Sp-600125 220.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein