Showing entry for Cyclin-G-associated kinase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004118
Protein NameCyclin-G-associated kinase
Uniport IdO14976
GeneGAK
Gene Id2580
DomainPkinase; PTEN_C2
Pfam PF00069   PF10409  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007049 cell cycle
Biological Process GO:0051085 chaperone cofactor-dependent protein refolding
Biological Process GO:0072318 clathrin coat disassembly
Biological Process GO:1905224 clathrin-coated pit assembly
Biological Process GO:0072583 clathrin-dependent endocytosis
Biological Process GO:0007029 endoplasmic reticulum organization
Biological Process GO:0007030 Golgi organization
Biological Process GO:0090160 Golgi to lysosome transport
Biological Process GO:0061024 membrane organization
Biological Process GO:0010977 negative regulation of neuron projection development
Biological Process GO:0034067 protein localization to Golgi apparatus
Biological Process GO:0072659 protein localization to plasma membrane
Biological Process GO:0006898 receptor-mediated endocytosis
Biological Process GO:0016191 synaptic vesicle uncoating
molecular function GO:0005524 ATP binding
molecular function GO:0051087 chaperone binding
molecular function GO:0030276 clathrin binding
molecular function GO:0030332 cyclin binding
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005925 focal adhesion
cellular component GO:0005794 Golgi apparatus
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0098793 presynapse
cellular component GO:0031982 vesicle
Reactome
Pathway Id Pathway Name
R-HSA-199991 Membrane Trafficking
R-HSA-199992 trans-Golgi Network Vesicle Budding
R-HSA-432722 Golgi Associated Vesicle Biogenesis
R-HSA-5653656 Vesicle-mediated transport
R-HSA-8856828 Clathrin-mediated endocytosis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0040822 BXGD002885 Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0200635 BXGD004041 Lymphocyte Count measurement
C0202236 BXGD004086 Triglycerides measurement
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0751772 BXGD010583 REM Sleep Behavior Disorder Nervous System Diseases; Mental Disorders
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0001380 Succinic acid 118.09
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein