Showing entry for Peroxisomal acyl-coenzyme A oxidase 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004143
Protein NamePeroxisomal acyl-coenzyme A oxidase 3
Uniport IdO15254
GeneACOX3
Gene Id8310
DomainACOX; Acyl-CoA_dh_M
Pfam PF01756   PF02770  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00071 Fatty acid degradation
1. Metabolism 1.6 Metabolism of other amino acids hsa00410 beta-Alanine metabolism
1. Metabolism 1.3 Lipid metabolism hsa00592 alpha-Linolenic acid metabolism
1. Metabolism 1.1 Carbohydrate metabolism hsa00640 Propanoate metabolism
1. Metabolism 1.3 Lipid metabolism hsa01040 Biosynthesis of unsaturated fatty acids
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
1. Metabolism 1.0 Global and overview maps hsa01200 Carbon metabolism
1. Metabolism 1.0 Global and overview maps hsa01212 Fatty acid metabolism
5. Organismal Systems 5.2 Endocrine system hsa03320 PPAR signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04024 cAMP signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04146 Peroxisome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase
Biological Process GO:0055088 lipid homeostasis
Biological Process GO:0006625 protein targeting to peroxisome
molecular function GO:0003997 acyl-CoA oxidase activity
molecular function GO:0071949 FAD binding
molecular function GO:0005504 fatty acid binding
molecular function GO:0050660 flavin adenine dinucleotide binding
molecular function GO:0016402 pristanoyl-CoA oxidase activity
cellular component GO:0005829 cytosol
cellular component GO:0016020 membrane
cellular component GO:0005782 peroxisomal matrix
cellular component GO:0005777 peroxisome
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-389887 Beta-oxidation of pristanoyl-CoA
R-HSA-390918 Peroxisomal lipid metabolism
R-HSA-556833 Metabolism of lipids
R-HSA-8978868 Fatty acid metabolism
R-HSA-9033241 Peroxisomal protein import
R-HSA-9033241 Peroxisomal protein import
R-HSA-9609507 Protein localization
R-HSA-9609507 Protein localization
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0019193 BXGD001299 Hepatitis, Toxic Digestive System Diseases; Chemically-Induced Disorders
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C1262760 BXGD011886 Hepatitis, Drug-Induced Digestive System Diseases; Chemically-Induced Disorders
C3658290 BXGD019256 Drug-Induced Acute Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4277682 BXGD022376 Chemical and Drug Induced Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4279912 BXGD022378 Chemically-Induced Liver Toxicity Digestive System Diseases; Chemically-Induced Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein