protein

Showing entry for Tumor necrosis factor ligand superfamily member 11

General Target Information
BXGT Id	BXGT004518
Protein Name	Tumor necrosis factor ligand superfamily member 11
Uniport Id	O35235
Gene	Tnfsf11
Gene Id	21943
Domain	TNF
Pfam	PF00229
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0007257	activation of JUN kinase activity
Biological Process	GO:0009887	animal organ morphogenesis
Biological Process	GO:0060348	bone development
Biological Process	GO:0045453	bone resorption
Biological Process	GO:0055074	calcium ion homeostasis
Biological Process	GO:0019722	calcium-mediated signaling
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor
Biological Process	GO:0019221	cytokine-mediated signaling pathway
Biological Process	GO:0070371	ERK1 and ERK2 cascade
Biological Process	GO:0006955	immune response
Biological Process	GO:0048535	lymph node development
Biological Process	GO:0060749	mammary gland alveolus development
Biological Process	GO:0033598	mammary gland epithelial cell proliferation
Biological Process	GO:0002548	monocyte chemotaxis
Biological Process	GO:0001503	ossification
Biological Process	GO:0036035	osteoclast development
Biological Process	GO:0030316	osteoclast differentiation
Biological Process	GO:0002158	osteoclast proliferation
Biological Process	GO:0038001	paracrine signaling
Biological Process	GO:0045780	positive regulation of bone resorption
Biological Process	GO:0051466	positive regulation of corticotropin-releasing hormone secretion
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity
Biological Process	GO:0071848	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
Biological Process	GO:0071812	positive regulation of fever generation by positive regulation of prostaglandin secretion
Biological Process	GO:0010628	positive regulation of gene expression
Biological Process	GO:0034112	positive regulation of homotypic cell-cell adhesion
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process	GO:1902533	positive regulation of intracellular signal transduction
Biological Process	GO:0046330	positive regulation of JNK cascade
Biological Process	GO:0043406	positive regulation of MAP kinase activity
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity
Biological Process	GO:2001206	positive regulation of osteoclast development
Biological Process	GO:0045672	positive regulation of osteoclast differentiation
Biological Process	GO:0042327	positive regulation of phosphorylation
Biological Process	GO:0051897	positive regulation of protein kinase B signaling
Biological Process	GO:0050870	positive regulation of T cell activation
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II
Biological Process	GO:1904616	regulation of actin binding
Biological Process	GO:0045670	regulation of osteoclast differentiation
Biological Process	GO:0071847	TNFSF11-mediated signaling pathway
Biological Process	GO:0044691	tooth eruption
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway
molecular function	GO:0005125	cytokine activity
molecular function	GO:0042802	identical protein binding
molecular function	GO:0005164	tumor necrosis factor receptor binding
molecular function	GO:0032813	tumor necrosis factor receptor superfamily binding
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005615	extracellular space
cellular component	GO:0016021	integral component of membrane
cellular component	GO:0005886	plasma membrane

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0003705	Chloride		35.45
BXGC0005915	Formononetin		268.27
BXGC0036869	Harpagoside		494.18
BXGC0039829	praeruptorin A		386.14
BXGC0044857	Sp-600125		220.06

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}