Showing entry for Tumor necrosis factor receptor superfamily member 11A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004523
Protein NameTumor necrosis factor receptor superfamily member 11A
Uniport IdO35305
GeneTnfrsf11a
Gene Id21934
DomainRANK_CRD_2; TNFR_c6
Pfam PF18278   PF00020  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0060086 circadian temperature homeostasis
Biological Process GO:0048535 lymph node development
Biological Process GO:0060749 mammary gland alveolus development
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0072674 multinuclear osteoclast differentiation
Biological Process GO:0001503 ossification
Biological Process GO:0030316 osteoclast differentiation
Biological Process GO:0045780 positive regulation of bone resorption
Biological Process GO:0051091 positive regulation of DNA-binding transcription factor activity
Biological Process GO:0071848 positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
Biological Process GO:0071812 positive regulation of fever generation by positive regulation of prostaglandin secretion
Biological Process GO:0043507 positive regulation of JUN kinase activity
Biological Process GO:0051092 positive regulation of NF-kappaB transcription factor activity
Biological Process GO:0034097 response to cytokine
Biological Process GO:0070555 response to interleukin-1
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0009314 response to radiation
Biological Process GO:0034612 response to tumor necrosis factor
Biological Process GO:0071847 TNFSF11-mediated signaling pathway
Biological Process GO:0033209 tumor necrosis factor-mediated signaling pathway
molecular function GO:0019955 cytokine binding
molecular function GO:0046872 metal ion binding
molecular function GO:0004888 transmembrane signaling receptor activity
molecular function GO:0005031 tumor necrosis factor-activated receptor activity
cellular component GO:0009986 cell surface
cellular component GO:0005829 cytosol
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein