protein

Showing entry for Multidrug resistance-associated protein 1

General Target Information
BXGT Id	BXGT004525
Protein Name	Multidrug resistance-associated protein 1
Uniport Id	O35379
Gene	Abcc1
Gene Id	17250
Domain	ABC_membrane; ABC_tran
Pfam	PF00664 PF00005
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0060326	cell chemotaxis
Biological Process	GO:1904646	cellular response to amyloid-beta
Biological Process	GO:0140115	export across plasma membrane
Biological Process	GO:0034775	glutathione transmembrane transport
Biological Process	GO:0071716	leukotriene transport
Biological Process	GO:0015911	long-chain fatty acid import across plasma membrane
Biological Process	GO:0060548	negative regulation of cell death
Biological Process	GO:1901215	negative regulation of neuron death
Biological Process	GO:0033700	phospholipid efflux
Biological Process	GO:0045332	phospholipid translocation
Biological Process	GO:0030335	positive regulation of cell migration
Biological Process	GO:0050729	positive regulation of inflammatory response
Biological Process	GO:0042493	response to drug
Biological Process	GO:0006979	response to oxidative stress
Biological Process	GO:0099039	sphingolipid translocation
Biological Process	GO:0070633	transepithelial transport
Biological Process	GO:0055085	transmembrane transport
Biological Process	GO:1990961	xenobiotic detoxification by transmembrane export across the plasma membrane
Biological Process	GO:0042908	xenobiotic transport
molecular function	GO:0140359	ABC-type transmembrane transporter activity
molecular function	GO:0042887	amide transmembrane transporter activity
molecular function	GO:0016887	ATPase activity
molecular function	GO:0015431	ATPase-coupled glutathione S-conjugate transmembrane transporter activity
molecular function	GO:0034040	ATPase-coupled lipid transmembrane transporter activity
molecular function	GO:0042626	ATPase-coupled transmembrane transporter activity
molecular function	GO:0008559	ATPase-coupled xenobiotic transmembrane transporter activity
molecular function	GO:0005524	ATP binding
molecular function	GO:0015562	efflux transmembrane transporter activity
molecular function	GO:0034634	glutathione transmembrane transporter activity
molecular function	GO:0005324	long-chain fatty acid transporter activity
molecular function	GO:0042910	xenobiotic transmembrane transporter activity
cellular component	GO:0016324	apical plasma membrane
cellular component	GO:0009925	basal plasma membrane
cellular component	GO:0016323	basolateral plasma membrane
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005887	integral component of plasma membrane
cellular component	GO:0016328	lateral plasma membrane
cellular component	GO:0016020	membrane
cellular component	GO:0005886	plasma membrane

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0003631	Phytosterol		414.72
BXGC0027374	Glyburide		493.14
BXGC0030138	Colchicine		399.17
BXGC0034768	Vincristine		824.4
BXGC0034783	Doxorubicin		543.17

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}