Showing entry for Galanin receptor type 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004604
Protein NameGalanin receptor type 2
Uniport IdO43603
GeneGALR2
Gene Id8811
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:0007631 feeding behavior
Biological Process GO:0090663 galanin-activated signaling pathway
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0043647 inositol phosphate metabolic process
Biological Process GO:0007611 learning or memory
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0006936 muscle contraction
Biological Process GO:0007194 negative regulation of adenylate cyclase activity
Biological Process GO:0031175 neuron projection development
Biological Process GO:0007218 neuropeptide signaling pathway
Biological Process GO:0046488 phosphatidylinositol metabolic process
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:1902608 positive regulation of large conductance calcium-activated potassium channel activity
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
molecular function GO:0004966 galanin receptor activity
molecular function GO:0008528 G protein-coupled peptide receptor activity
molecular function GO:0042923 neuropeptide binding
molecular function GO:0017046 peptide hormone binding
cellular component GO:0005929 cilium
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011574 BXGD000731 Involutional Depression Mental Disorders
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0031511 BXGD002304 Pheochromocytoma Neoplasms
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0432215 BXGD008739 Progressive pseudorheumatoid dysplasia Musculoskeletal Diseases
C0494491 BXGD009032 Mononeuropathies Nervous System Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0751791 BXGD010595 Reflex Epilepsy, Audiogenic Nervous System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1571983 BXGD013425 Involutional paraphrenia Mental Disorders
C1571984 BXGD013426 Psychosis, Involutional Mental Disorders
C2349952 BXGD017065 Oropharyngeal Carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4551683 BXGD023389 Adrenal Gland Pheochromocytoma Neoplasms; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0038807 curine 594.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein