Showing entry for Cytohesin-3



                       
General Target Information
BXGT IdBXGT004619
Protein NameCytohesin-3
Uniport IdO43739
GeneCYTH3
Gene Id9265
DomainPH; Sec7
Pfam PF00169   PF01369  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04072 Phospholipase D signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0090162 establishment of epithelial cell polarity
Biological Process GO:0048193 Golgi vesicle transport
Biological Process GO:0045785 positive regulation of cell adhesion
Biological Process GO:0032012 regulation of ARF protein signal transduction
molecular function GO:0005086 ARF guanyl-nucleotide exchange factor activity
molecular function GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
cellular component GO:0005912 adherens junction
cellular component GO:0005923 bicellular tight junction
cellular component GO:0005829 cytosol
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0000139 Golgi membrane
cellular component GO:0005654 nucleoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0001726 ruffle
Reactome
Pathway Id Pathway Name
R-HSA-199991 Membrane Trafficking
R-HSA-5653656 Vesicle-mediated transport
R-HSA-6811438 Intra-Golgi traffic
R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018810 BXGD001231 heart rate
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C4022792 BXGD020999 Reduced ejection fraction
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein