Showing entry for [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004736
Protein Name[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial
Uniport IdO54937
GenePdk4
Gene Id89813
DomainBCDHK_Adom3; HATPase_c
Pfam PF10436   PF02518  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006086 acetyl-CoA biosynthetic process from pyruvate
Biological Process GO:0071398 cellular response to fatty acid
Biological Process GO:0009267 cellular response to starvation
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0006006 glucose metabolic process
Biological Process GO:0008286 insulin receptor signaling pathway
Biological Process GO:2000811 negative regulation of anoikis
Biological Process GO:1904183 negative regulation of pyruvate dehydrogenase activity
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0072593 reactive oxygen species metabolic process
Biological Process GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate
Biological Process GO:0045124 regulation of bone resorption
Biological Process GO:0010565 regulation of cellular ketone metabolic process
Biological Process GO:0042304 regulation of fatty acid biosynthetic process
Biological Process GO:0046320 regulation of fatty acid oxidation
Biological Process GO:0010906 regulation of glucose metabolic process
Biological Process GO:0006885 regulation of pH
Biological Process GO:0042594 response to starvation
molecular function GO:0005524 ATP binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0013795 phenylglyoxylic acid 150.03
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein