Showing entry for Nuclear factor erythroid 2-related factor 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004738
Protein NameNuclear factor erythroid 2-related factor 2
Uniport IdO54968
GeneNfe2l2
Gene Id83619
DomainbZIP_Maf
Pfam PF03131  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046223 aflatoxin catabolic process
Biological Process GO:0007568 aging
Biological Process GO:0045454 cell redox homeostasis
Biological Process GO:1904385 cellular response to angiotensin
Biological Process GO:0071280 cellular response to copper ion
Biological Process GO:0035690 cellular response to drug
Biological Process GO:0071498 cellular response to fluid shear stress
Biological Process GO:0042149 cellular response to glucose starvation
Biological Process GO:0070301 cellular response to hydrogen peroxide
Biological Process GO:0071456 cellular response to hypoxia
Biological Process GO:0071499 cellular response to laminar fluid shear stress
Biological Process GO:0034599 cellular response to oxidative stress
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0030968 endoplasmic reticulum unfolded protein response
Biological Process GO:0006954 inflammatory response
Biological Process GO:0010667 negative regulation of cardiac muscle cell apoptotic process
Biological Process GO:0060548 negative regulation of cell death
Biological Process GO:2000352 negative regulation of endothelial cell apoptotic process
Biological Process GO:1902037 negative regulation of hematopoietic stem cell differentiation
Biological Process GO:1903206 negative regulation of hydrogen peroxide-induced cell death
Biological Process GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
Biological Process GO:1904753 negative regulation of vascular associated smooth muscle cell migration
Biological Process GO:0036499 PERK-mediated unfolded protein response
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:0030194 positive regulation of blood coagulation
Biological Process GO:0043536 positive regulation of blood vessel endothelial cell migration
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0046326 positive regulation of glucose import
Biological Process GO:1903788 positive regulation of glutathione biosynthetic process
Biological Process GO:0010976 positive regulation of neuron projection development
Biological Process GO:2000379 positive regulation of reactive oxygen species metabolic process
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
Biological Process GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
Biological Process GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress
Biological Process GO:0010499 proteasomal ubiquitin-independent protein catabolic process
Biological Process GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0045995 regulation of embryonic development
Biological Process GO:2000121 regulation of removal of superoxide radicals
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0042493 response to drug
Biological Process GO:0034976 response to endoplasmic reticulum stress
molecular function GO:0003677 DNA binding
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0019904 protein domain specific binding
molecular function GO:0001102 RNA polymerase II activating transcription factor binding
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:0001221 transcription cofactor binding
molecular function GO:0008134 transcription factor binding
molecular function GO:0000976 transcription regulatory region sequence-specific DNA binding
cellular component GO:0005813 centrosome
cellular component GO:0000785 chromatin
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005794 Golgi apparatus
cellular component GO:0042025 host cell nucleus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0032993 protein-DNA complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004576 2-tert-Butyl-1,4-benzenediol 166.22
BXGC0006079 Yangonin 258.27
BXGC0006466 Oleanolic acid 456.71
BXGC0012483 Piperitol 356.13
BXGC0016444 Asarinin 354.11
BXGC0016714 Sesamin dicatechol 330.11
BXGC0022310 Sesamin 354.11
BXGC0025325 Methysticin 274.08
BXGC0034326 Episesamin Dicatechol 330.11
BXGC0038322 Kavain 230.09
BXGC0044857 Sp-600125 220.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein