Showing entry for Protein-tyrosine sulfotransferase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004880
Protein NameProtein-tyrosine sulfotransferase 1
Uniport IdO60507
GeneTPST1
Gene Id8460
DomainSulfotransfer_3
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process
Biological Process GO:0006954 inflammatory response
Biological Process GO:0006478 peptidyl-tyrosine sulfation
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0008476 protein-tyrosine sulfotransferase activity
molecular function GO:0008146 sulfotransferase activity
cellular component GO:0005794 Golgi apparatus
cellular component GO:0000139 Golgi membrane
cellular component GO:0030173 integral component of Golgi membrane
cellular component GO:0016020 membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-156580 Phase II - Conjugation of compounds
R-HSA-156584 Cytosolic sulfonation of small molecules
R-HSA-163841 Gamma carboxylation, hypusine formation and arylsulfatase activation
R-HSA-1643685 Disease
R-HSA-211859 Biological oxidations
R-HSA-392499 Metabolism of proteins
R-HSA-597592 Post-translational protein modification
R-HSA-9651496 Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)
R-HSA-9662001 Defective factor VIII causes hemophilia A
R-HSA-9671793 Diseases of hemostasis
R-HSA-9674519 Defective F8 sulfation at Y1699
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003868 BXGD000233 Arthritis, Gouty Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0018099 BXGD001172 Gout Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0023508 BXGD001675 White Blood Cell Count procedure
C0027651 BXGD002009 Neoplasms Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0272170 BXGD006312 Shwachman syndrome
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein