Showing entry for UDP-glucose 6-dehydrogenase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004894
Protein NameUDP-glucose 6-dehydrogenase
Uniport IdO60701
GeneUGDH
Gene Id7358
DomainUDPG_MGDP_dh; UDPG_MGDP_dh_C; UDPG_MGDP_dh_N
Pfam PF00984   PF03720   PF03721  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00040 Pentose and glucuronate interconversions
1. Metabolism 1.1 Carbohydrate metabolism hsa00053 Ascorbate and aldarate metabolism
1. Metabolism 1.1 Carbohydrate metabolism hsa00520 Amino sugar and nucleotide sugar metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0005975 carbohydrate metabolic process
Biological Process GO:0030206 chondroitin sulfate biosynthetic process
Biological Process GO:0001702 gastrulation with mouth forming second
Biological Process GO:0006024 glycosaminoglycan biosynthetic process
Biological Process GO:0015012 heparan sulfate proteoglycan biosynthetic process
Biological Process GO:0034214 protein hexamerization
Biological Process GO:0006065 UDP-glucuronate biosynthetic process
molecular function GO:0042802 identical protein binding
molecular function GO:0051287 NAD binding
molecular function GO:0003979 UDP-glucose 6-dehydrogenase activity
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-156580 Phase II - Conjugation of compounds
R-HSA-156588 Glucuronidation
R-HSA-173599 Formation of the active cofactor, UDP-glucuronate
R-HSA-211859 Biological oxidations
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002875 BXGD000135 Cooley's anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0005283 BXGD000308 beta Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0010709 BXGD000689 Cyst Pathological Conditions, Signs and Symptoms; Neoplasms
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017536 BXGD001114 Giardiasis Digestive System Diseases; Infections
C0017636 BXGD001131 Glioblastoma Neoplasms
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020501 BXGD001409 Primary Hyperoxaluria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0022346 BXGD001537 Icterus Pathological Conditions, Signs and Symptoms
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029182 BXGD002121 orbit (eye disorders) Eye Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0275524 BXGD006376 Coinfection Infections
C0343386 BXGD007620 Clostridium difficile infection Infections
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0474808 BXGD008959 Follicular neoplasm Neoplasms
C0543888 BXGD009300 Epileptic encephalopathy Nervous System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0687720 BXGD009844 Central Diabetes Insipidus Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1411966 BXGD013047 Clostridium; difficile (disorder)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1704436 BXGD013564 Peripheral Arterial Diseases Cardiovascular Diseases
C1864903 BXGD016270 Hyperinsulinemic hypoglycemia Nutritional and Metabolic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3805278 BXGD019474 Extrahepatic Cholangiocarcinoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0002616 Copper 63.55
BXGC0003416 Udp-glucose 566.3
BXGC0003705 Chloride 35.45
BXGC0023687 (S)-(+)-1,2-Propanediol 76.05
BXGC0030612 tetraethylene glycol 194.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein