Showing entry for ATP-binding cassette sub-family C member 9


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004896
Protein NameATP-binding cassette sub-family C member 9
Uniport IdO60706
GeneABCC9
Gene Id10060
DomainABC_membrane; ABC_tran
Pfam PF00664   PF00005  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.1 Membrane transport hsa02010 ABC transporters
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0061337 cardiac conduction
Biological Process GO:0098655 cation transmembrane transport
Biological Process GO:0051607 defense response to virus
Biological Process GO:0098662 inorganic cation transmembrane transport
Biological Process GO:1990573 potassium ion import across plasma membrane
Biological Process GO:0071805 potassium ion transmembrane transport
Biological Process GO:1903779 regulation of cardiac conduction
Biological Process GO:0033198 response to ATP
Biological Process GO:0055085 transmembrane transport
Biological Process GO:0150104 transport across blood-brain barrier
molecular function GO:0016887 ATPase activity
molecular function GO:0019829 ATPase-coupled cation transmembrane transporter activity
molecular function GO:0042626 ATPase-coupled transmembrane transporter activity
molecular function GO:0005524 ATP binding
molecular function GO:0044325 ion channel binding
molecular function GO:0005267 potassium channel activity
molecular function GO:0015459 potassium channel regulator activity
molecular function GO:0008281 sulfonylurea receptor activity
cellular component GO:0008282 inward rectifying potassium channel
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0031004 potassium ion-transporting ATPase complex
cellular component GO:0030017 sarcomere
Reactome
Pathway Id Pathway Name
R-HSA-112316 Neuronal System
R-HSA-1296025 ATP sensitive Potassium channels
R-HSA-1296065 Inwardly rectifying K+ channels
R-HSA-1296071 Potassium Channels
R-HSA-1643685 Disease
R-HSA-382551 Transport of small molecules
R-HSA-382556 ABC-family proteins mediated transport
R-HSA-397014 Muscle contraction
R-HSA-5576891 Cardiac conduction
R-HSA-5578775 Ion homeostasis
R-HSA-5619084 ABC transporter disorders
R-HSA-5619115 Disorders of transmembrane transporters
R-HSA-5678420 Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000772 BXGD000009 Multiple congenital anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0002963 BXGD000161 Angina Pectoris, Variant Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003868 BXGD000233 Arthritis, Gouty Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0005612 BXGD000317 Birth Weight Pathological Conditions, Signs and Symptoms
C0005744 BXGD000330 Blepharophimosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0006111 BXGD000369 Brain Diseases Nervous System Diseases
C0007193 BXGD000451 Cardiomyopathy, Dilated Cardiovascular Diseases
C0007194 BXGD000452 Hypertrophic Cardiomyopathy Cardiovascular Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010073 BXGD000650 Coronary Artery Vasospasm Cardiovascular Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013274 BXGD000809 Patent ductus arteriosus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0014170 BXGD000902 Endometrial Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0018099 BXGD001172 Gout Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0018564 BXGD001204 Hand deformities Musculoskeletal Diseases
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018799 BXGD001224 Heart Diseases Cardiovascular Diseases
C0018800 BXGD001225 Cardiomegaly Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019572 BXGD001338 Hirsutism Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020555 BXGD001431 Hypertrichosis Skin and Connective Tissue Diseases
C0023787 BXGD001698 Lipodystrophy Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0023976 BXGD001724 Long QT Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0024236 BXGD001752 Lymphedema Hemic and Lymphatic Diseases
C0024421 BXGD001770 Macroglossia Stomatognathic Diseases
C0024433 BXGD001771 Macrostomia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0025990 BXGD001884 Micrognathism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0026106 BXGD001889 Mild Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027404 BXGD001984 Narcolepsy Nervous System Diseases; Mental Disorders
C0029422 BXGD002142 Osteochondrodysplasias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030591 BXGD002247 Paroxysmal ventricular tachycardia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0031039 BXGD002274 Pericardial effusion Cardiovascular Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037052 BXGD002662 Sick Sinus Syndrome Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0039070 BXGD002787 Syncope Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0039240 BXGD002804 Supraventricular tachycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0040412 BXGD002860 Fissured tongue Stomatognathic Diseases
C0042510 BXGD002987 Ventricular Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0042514 BXGD002989 Tachycardia, Ventricular Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0043202 BXGD003037 Wolff-Parkinson-White Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0085612 BXGD003204 Ventricular arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085614 BXGD003205 First degree atrioventricular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085615 BXGD003206 Right bundle branch block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0149630 BXGD003334 Bicuspid aortic valve Cardiovascular Diseases
C0149940 BXGD003391 Sciatic Neuropathy Nervous System Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0151879 BXGD003496 Shortened QT interval Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0155707 BXGD003813 Trifascicular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0162285 BXGD003928 Edema of eyelid Female Urogenital Diseases and Pregnancy Complications; Eye Diseases; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases; Cardiovascular Diseases
C0221352 BXGD004444 Syndactyly of fingers Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases
C0221355 BXGD004447 Macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0231230 BXGD004485 Fatigability
C0234119 BXGD004622 Neuromuscular inhibition
C0235480 BXGD004751 Paroxysmal atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0235864 BXGD004780 Congenital hypertrichosis lanuginosa Skin and Connective Tissue Diseases
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0239137 BXGD004965 Coxa valga Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0240543 BXGD005042 Bulbous nose
C0241005 BXGD005072 Creatine phosphokinase serum increased
C0241165 BXGD005083 Thick skin
C0241240 BXGD005089 Tall stature
C0241654 BXGD005104 Abnormal heart valve morphology Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0243050 BXGD005212 Cardiovascular Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0264694 BXGD005413 Chronic myocardial ischemia Cardiovascular Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0340427 BXGD007329 Familial dilated cardiomyopathy Cardiovascular Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0376480 BXGD007998 Gingival Overgrowth Stomatognathic Diseases
C0410528 BXGD008430 Skeletal dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0410702 BXGD008447 Adolescent idiopathic scoliosis Musculoskeletal Diseases
C0424574 BXGD008534 Duration of sleep
C0426790 BXGD008577 Narrow thorax
C0426870 BXGD008592 Large hand
C0426886 BXGD008594 Tapering fingers (finding)
C0427515 BXGD008619 Neutrophil abnormality
C0431447 BXGD008690 Synophrys Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0432072 BXGD008718 Dysmorphic features
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0476403 BXGD008992 Electromyogram abnormal
C0520886 BXGD009118 ST segment elevation (finding) Cardiovascular Diseases
C0521525 BXGD009139 Short neck
C0541764 BXGD009259 Delayed bone age
C0545053 BXGD009323 Advanced bone age
C0678230 BXGD009750 Congenital Epicanthus
C0795905 BXGD010761 Cantu syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases
C0796280 BXGD010831 Acromegaloid facial appearance syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases
C0878486 BXGD011364 Arteriolosclerosis Cardiovascular Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C1142166 BXGD011736 Brugada Syndrome (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1280433 BXGD012125 Lipoatrophy Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C1306503 BXGD012363 Congenital exomphalos Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1504404 BXGD013141 Hippocampal sclerosis
C1720983 BXGD013698 Channelopathies Pathological Conditions, Signs and Symptoms
C1836542 BXGD014129 Depressed nasal bridge
C1836543 BXGD014130 Thick vermilion border
C1837260 BXGD014214 Prominent forehead
C1837461 BXGD014234 SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
C1837839 BXGD014280 CARDIOMYOPATHY, DILATED, 1O Cardiovascular Diseases
C1839739 BXGD014400 Thick lower lip vermilion
C1839798 BXGD014410 Long nose
C1839829 BXGD014413 Short distal phalanx of finger
C1840077 BXGD014434 Anteverted nostril
C1842060 BXGD014491 Prominent supraorbital ridges
C1842366 BXGD014512 Low anterior hairline
C1843367 BXGD014576 Poor school performance
C1843677 BXGD014601 Large sella turcica
C1843687 BXGD014602 ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1844704 BXGD014665 Platyspondyly
C1844809 BXGD014677 Thick nasal alae
C1845847 BXGD014760 Coarse facial features Pathological Conditions, Signs and Symptoms
C1846423 BXGD014812 Thick upper lip vermilion
C1848395 BXGD014921 Large for gestational age Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C1848654 BXGD014958 Broad ribs
C1849039 BXGD014999 Metaphyseal widening
C1849211 BXGD015023 Generalized hirsutism Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C1849265 BXGD015028 Overgrowth
C1849367 BXGD015046 Nasal bridge wide
C1853246 BXGD015323 Eversion of lower lip
C1853487 BXGD015340 Thick eyebrow
C1853738 BXGD015357 Long eyelashes
C1855665 BXGD015524 Ovoid vertebral bodies
C1855728 BXGD015536 Low posterior hairline
C1855889 BXGD015556 Widened posterior fossa
C1855895 BXGD015557 Erlenmeyer flask deformity of the femurs
C1855899 BXGD015558 Broad first metatarsal
C1855900 BXGD015559 HYPERTRICHOSIS, CONGENITAL GENERALIZED Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C1855901 BXGD015560 Congenital hypertrophy of left ventricle Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1857679 BXGD015735 Sloping forehead
C1857953 BXGD015759 Deep plantar creases
C1865014 BXGD016282 Long philtrum
C1865992 BXGD016359 Short hallux
C1867131 BXGD016440 Broad hallux
C1868085 BXGD016486 Craniofacial hyperostosis
C1868571 BXGD016508 Highly arched eyebrow
C2243051 BXGD017008 Large head (disorder)
C2673653 BXGD017219 Cuboid-shaped vertebral bodies
C2673670 BXGD017220 Curly eyelashes
C2931193 BXGD017973 Prinzmetal's variant angina Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C2936812 BXGD018140 Congenital hypertrichosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C3279695 BXGD018772 ATRIAL FIBRILLATION, FAMILIAL, 12
C3553764 BXGD019187 Joint hyperflexibility
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3715208 BXGD019451 AV Block First Degree by ECG Finding Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C4021343 BXGD020613 Broad hallux phalanx
C4021785 BXGD020778 Abnormality of the metacarpal bones Musculoskeletal Diseases
C4023921 BXGD021278 Oral synechia
C4024617 BXGD021346 Hypoplastic ischiopubic rami
C4025009 BXGD021524 Impaired myocardial contractility
C4025756 BXGD021778 Abnormal aortic morphology
C4025814 BXGD021806 Abnormality of the metaphysis
C4054546 BXGD021984 Melanocortin 4 Receptor Deficiency
C4551584 BXGD023362 Brain atrophy Nervous System Diseases
C4551675 BXGD023384 Keratoderma, Palmoplantar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0027374 Glyburide 493.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein