Showing entry for Matrix metalloproteinase-20


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004905
Protein NameMatrix metalloproteinase-20
Uniport IdO60882
GeneMMP20
Gene Id9313
DomainHemopexin; Peptidase_M10; PG_binding_1
Pfam PF00045   PF00413   PF01471  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0097186 amelogenesis
Biological Process GO:0030574 collagen catabolic process
Biological Process GO:0022617 extracellular matrix disassembly
Biological Process GO:0030198 extracellular matrix organization
Biological Process GO:0030163 protein catabolic process
Biological Process GO:0006508 proteolysis
Biological Process GO:0070173 regulation of enamel mineralization
molecular function GO:0004222 metalloendopeptidase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0031012 extracellular matrix
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
R-HSA-1442490 Collagen degradation
R-HSA-1474228 Degradation of the extracellular matrix
R-HSA-1474228 Degradation of the extracellular matrix
R-HSA-1474244 Extracellular matrix organization
R-HSA-1474244 Extracellular matrix organization
R-HSA-1474290 Collagen formation
R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0000846 BXGD000015 Agenesis
C0002452 BXGD000116 Amelogenesis Imperfecta Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007873 BXGD000500 Uterine Cervical Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0011334 BXGD000716 Dental caries Stomatognathic Diseases
C0011430 BXGD000723 Dentin Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0011436 BXGD000726 Dentinogenesis Imperfecta Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0026618 BXGD001909 Dental Fluorosis, Acquired Stomatognathic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028878 BXGD002095 Odontogenesis Imperfecta Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0028880 BXGD002097 Odontogenic Tumors Neoplasms
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0333519 BXGD006958 Caries (morphologic abnormality) Pathological Conditions, Signs and Symptoms
C0399372 BXGD008240 Amelogenesis Imperfecta hypomaturation type Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0410632 BXGD008440 Schmorl's nodes Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0424574 BXGD008534 Duration of sleep
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0868847 BXGD011301 Hereditary disturbances in tooth structure, not elsewhere classified in ICD10CM
C0878500 BXGD011365 Intraepithelial Neoplasia Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2675858 BXGD017311 Amelogenesis Imperfecta, Hypomaturation Type, Iia2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C2981132 BXGD018208 Shell teeth Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C3665629 BXGD019297 Dental fluorosis
C3714731 BXGD019425 Early childhood caries Stomatognathic Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein