Showing entry for Bile salt export pump


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005057
Protein NameBile salt export pump
Uniport IdO70127
GeneAbcb11
Gene Id83569
DomainABC_membrane; ABC_tran
Pfam PF00664   PF00005  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015721 bile acid and bile salt transport
Biological Process GO:0008206 bile acid metabolic process
Biological Process GO:0038183 bile acid signaling pathway
Biological Process GO:0015722 canalicular bile acid transport
Biological Process GO:0035690 cellular response to drug
Biological Process GO:0042632 cholesterol homeostasis
Biological Process GO:0046618 drug export
Biological Process GO:0017144 drug metabolic process
Biological Process GO:0006855 drug transmembrane transport
Biological Process GO:0006631 fatty acid metabolic process
Biological Process GO:0055088 lipid homeostasis
Biological Process GO:0055091 phospholipid homeostasis
Biological Process GO:0120189 positive regulation of bile acid secretion
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:1904251 regulation of bile acid metabolic process
Biological Process GO:0120188 regulation of bile acid secretion
Biological Process GO:0031998 regulation of fatty acid beta-oxidation
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:1904486 response to 17alpha-ethynylestradiol
Biological Process GO:0042493 response to drug
Biological Process GO:0043627 response to estrogen
Biological Process GO:0045471 response to ethanol
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0006979 response to oxidative stress
Biological Process GO:0055085 transmembrane transport
molecular function GO:0016887 ATPase activity
molecular function GO:0015432 ATPase-coupled bile acid transmembrane transporter activity
molecular function GO:0042626 ATPase-coupled transmembrane transporter activity
molecular function GO:0008559 ATPase-coupled xenobiotic transmembrane transporter activity
molecular function GO:0005524 ATP binding
molecular function GO:0015125 bile acid transmembrane transporter activity
molecular function GO:0015126 canalicular bile acid transmembrane transporter activity
molecular function GO:0015144 carbohydrate transmembrane transporter activity
cellular component GO:0045177 apical part of cell
cellular component GO:0016324 apical plasma membrane
cellular component GO:0009986 cell surface
cellular component GO:0005768 endosome
cellular component GO:0005794 Golgi apparatus
cellular component GO:0000139 Golgi membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0046581 intercellular canaliculus
cellular component GO:0046691 intracellular canaliculus
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0055037 recycling endosome
cellular component GO:0055038 recycling endosome membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000290 Pyridoxine 169.18
BXGC0000528 Salicylic acid 138.12
BXGC0000663 Papain 206.28
BXGC0002627 17alpha-ethynylestradiol 296.4
BXGC0003631 Phytosterol 414.72
BXGC0004667 Betaine 117.15
BXGC0005871 Dopamine 153.18
BXGC0006422 Mercenene 214.05
BXGC0012243 Ukonan D 151.16
BXGC0024988 Nifedipine 346.12
BXGC0027374 Glyburide 493.14
BXGC0030685 Physostigmine 275.16
BXGC0042222 Propranolol 259.16
BXGC0042596 Isoniazid 137.06
BXGC0044017 Verapamil 454.28
BXGC0053118 Streptomycin 581.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein