Showing entry for Axin-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005061
Protein NameAxin-1
Uniport IdO70239
GeneAxin1
Gene Id79257
DomainAXIN1_TNKS_BD; Axin_b-cat_bind; DIX; RGS
Pfam PF16646   PF08833   PF00778   PF00615  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032147 activation of protein kinase activity
Biological Process GO:0006915 apoptotic process
Biological Process GO:0048318 axial mesoderm development
Biological Process GO:0048320 axial mesoderm formation
Biological Process GO:0060070 canonical Wnt signaling pathway
Biological Process GO:0034622 cellular protein-containing complex assembly
Biological Process GO:0031122 cytoplasmic microtubule organization
Biological Process GO:0009950 dorsal/ventral axis specification
Biological Process GO:0009953 dorsal/ventral pattern formation
Biological Process GO:0071514 genetic imprinting
Biological Process GO:0060322 head development
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0090090 negative regulation of canonical Wnt signaling pathway
Biological Process GO:0045599 negative regulation of fat cell differentiation
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0051248 negative regulation of protein metabolic process
Biological Process GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter
Biological Process GO:0030178 negative regulation of Wnt signaling pathway
Biological Process GO:0006913 nucleocytoplasmic transport
Biological Process GO:0046330 positive regulation of JNK cascade
Biological Process GO:0043507 positive regulation of JUN kinase activity
Biological Process GO:0033138 positive regulation of peptidyl-serine phosphorylation
Biological Process GO:0010800 positive regulation of peptidyl-threonine phosphorylation
Biological Process GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Biological Process GO:0045732 positive regulation of protein catabolic process
Biological Process GO:0045860 positive regulation of protein kinase activity
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0031398 positive regulation of protein ubiquitination
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
Biological Process GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process
Biological Process GO:0051443 positive regulation of ubiquitin-protein transferase activity
Biological Process GO:0036342 post-anal tail morphogenesis
Biological Process GO:0030163 protein catabolic process
Biological Process GO:0000209 protein polyubiquitination
Biological Process GO:0060828 regulation of canonical Wnt signaling pathway
Biological Process GO:0001932 regulation of protein phosphorylation
Biological Process GO:0007605 sensory perception of sound
Biological Process GO:0016055 Wnt signaling pathway
molecular function GO:0070016 armadillo repeat domain binding
molecular function GO:0008013 beta-catenin binding
molecular function GO:0019899 enzyme binding
molecular function GO:0042802 identical protein binding
molecular function GO:0070411 I-SMAD binding
molecular function GO:0060090 molecular adaptor activity
molecular function GO:0002039 p53 binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0043621 protein self-association
molecular function GO:0070412 R-SMAD binding
molecular function GO:0035591 signaling adaptor activity
molecular function GO:0005102 signaling receptor binding
molecular function GO:0046332 SMAD binding
molecular function GO:0031625 ubiquitin protein ligase binding
cellular component GO:0030877 beta-catenin destruction complex
cellular component GO:0005938 cell cortex
cellular component GO:0071944 cell periphery
cellular component GO:0005737 cytoplasm
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0016328 lateral plasma membrane
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0032991 protein-containing complex
cellular component GO:1990909 Wnt signalosome
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004560 Benzoic acid 122.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein