Showing entry for Glycine receptor subunit alpha-3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005109
Protein NameGlycine receptor subunit alpha-3
Uniport IdO75311
GeneGLRA3
Gene Id8001
DomainNeur_chan_LBD; Neur_chan_memb
Pfam PF02931   PF02932  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:1902476 chloride transmembrane transport
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0050877 nervous system process
Biological Process GO:0007218 neuropeptide signaling pathway
Biological Process GO:0051260 protein homooligomerization
Biological Process GO:0042391 regulation of membrane potential
Biological Process GO:0043200 response to amino acid
Biological Process GO:0007165 signal transduction
Biological Process GO:0060012 synaptic transmission, glycinergic
molecular function GO:0016934 extracellularly glycine-gated chloride channel activity
molecular function GO:0016594 glycine binding
molecular function GO:0022852 glycine-gated chloride ion channel activity
molecular function GO:0046872 metal ion binding
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0004888 transmembrane signaling receptor activity
cellular component GO:0030425 dendrite
cellular component GO:0016935 glycine-gated chloride channel complex
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043005 neuron projection
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-112316 Neuronal System
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003868 BXGD000233 Arthritis, Gouty Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014548 BXGD000928 Epilepsy, Generalized Nervous System Diseases
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0035372 BXGD002544 Rett Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0234251 BXGD004645 Inflammatory pain Pathological Conditions, Signs and Symptoms
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0270850 BXGD006117 Idiopathic generalized epilepsy Nervous System Diseases
C0278704 BXGD006567 Malignant Childhood Neoplasm Neoplasms
C0936223 BXGD011477 Metastatic Prostate Carcinoma Neoplasms; Male Urogenital Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1282496 BXGD012147 Metastasis from malignant tumor of prostate
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000226 Glycine 75.07
BXGC0002374 Taurine 125.15
BXGC0003705 Chloride 35.45
BXGC0016417 Picrotoxin 310.11
BXGC0017719 Strychnine 334.17
BXGC0023873 Ivermectin 874.51
BXGC0038768 2,6-Ditert-Butylphenol 206.17
BXGC0040150 Cannabidiol 314.22
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein