protein

Showing entry for Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

General Target Information
BXGT Id	BXGT005282
Protein Name	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
Uniport Id	O88704
Gene	Hcn1
Gene Id	15165
Domain	cNMP_binding; Ion_trans; Ion_trans_N
Pfam	PF00027 PF00520 PF08412
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0045176	apical protein localization
Biological Process	GO:0071320	cellular response to cAMP
Biological Process	GO:0045759	negative regulation of action potential
Biological Process	GO:2001259	positive regulation of cation channel activity
Biological Process	GO:0071805	potassium ion transmembrane transport
Biological Process	GO:0051289	protein homotetramerization
Biological Process	GO:0003254	regulation of membrane depolarization
Biological Process	GO:1902630	regulation of membrane hyperpolarization
Biological Process	GO:0042391	regulation of membrane potential
Biological Process	GO:0051592	response to calcium ion
Biological Process	GO:0046549	retinal cone cell development
Biological Process	GO:0035725	sodium ion transmembrane transport
molecular function	GO:0030552	cAMP binding
molecular function	GO:0042802	identical protein binding
molecular function	GO:0005222	intracellular cAMP-activated cation channel activity
molecular function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
molecular function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
molecular function	GO:0044877	protein-containing complex binding
molecular function	GO:0008022	protein C-terminus binding
molecular function	GO:0022843	voltage-gated cation channel activity
molecular function	GO:0005249	voltage-gated potassium channel activity
molecular function	GO:0005248	voltage-gated sodium channel activity
cellular component	GO:0097440	apical dendrite
cellular component	GO:0030424	axon
cellular component	GO:0043679	axon terminus
cellular component	GO:0016323	basolateral plasma membrane
cellular component	GO:0009986	cell surface
cellular component	GO:0005737	cytoplasm
cellular component	GO:0030425	dendrite
cellular component	GO:0032590	dendrite membrane
cellular component	GO:0043198	dendritic shaft
cellular component	GO:0098855	HCN channel complex
cellular component	GO:0005887	integral component of plasma membrane
cellular component	GO:0043025	neuronal cell body
cellular component	GO:0005886	plasma membrane
cellular component	GO:0036477	somatodendritic compartment
cellular component	GO:0045202	synapse

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000988	3' 5'-cyclic AMP		329.21

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}