Showing entry for Apoptotic protease-activating factor 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005287
Protein NameApoptotic protease-activating factor 1
Uniport IdO88879
GeneApaf1
Gene Id11783
DomainAPAF1_C; CARD; NB-ARC; WD40
Pfam PF12894   PF17908   PF00619   PF00931   PF00400  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
Biological Process GO:0007568 aging
Biological Process GO:0007420 brain development
Biological Process GO:0010659 cardiac muscle cell apoptotic process
Biological Process GO:0030154 cell differentiation
Biological Process GO:0071560 cellular response to transforming growth factor beta stimulus
Biological Process GO:0030900 forebrain development
Biological Process GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Biological Process GO:0001822 kidney development
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0001843 neural tube closure
Biological Process GO:0051402 neuron apoptotic process
Biological Process GO:2001235 positive regulation of apoptotic signaling pathway
Biological Process GO:1902510 regulation of apoptotic DNA fragmentation
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0007584 response to nutrient
molecular function GO:0043531 ADP binding
molecular function GO:0005524 ATP binding
molecular function GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process
molecular function GO:0031072 heat shock protein binding
molecular function GO:0042802 identical protein binding
cellular component GO:0043293 apoptosome
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005634 nucleus
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002508 gamma-Butyrolactone 86.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein