Showing entry for Indolethylamine N-methyltransferase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005345
Protein NameIndolethylamine N-methyltransferase
Uniport IdO95050
GeneINMT
Gene Id11185
DomainNNMT_PNMT_TEMT
Pfam PF01234  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00380 Tryptophan metabolism
1. Metabolism 1.6 Metabolism of other amino acids hsa00450 Selenocompound metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009308 amine metabolic process
Biological Process GO:0032259 methylation
Biological Process GO:0009636 response to toxic substance
molecular function GO:0030748 amine N-methyltransferase activity
molecular function GO:0008170 N-methyltransferase activity
molecular function GO:0102707 S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity
molecular function GO:0004790 thioether S-methyltransferase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-2408522 Selenoamino acid metabolism
R-HSA-2408552 Methylation of MeSeH for excretion
R-HSA-71291 Metabolism of amino acids and derivatives
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0019569 BXGD001337 Hirschsprung Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0017352 Methylthioadenosine 297.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein