Showing entry for Cleavage and polyadenylation specificity factor subunit 4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005388
Protein NameCleavage and polyadenylation specificity factor subunit 4
Uniport IdO95639
GeneCPSF4
Gene Id10898
Domainzf-CCCH; zf-CCCH_3; zf-CCHC
Pfam PF00642   PF15663   PF00098  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa03015 mRNA surveillance pathway
6. Human Diseases 6.9 Infectious diseases: Viral hsa05164 Influenza A
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046778 modification by virus of host mRNA processing
Biological Process GO:0031124 mRNA 3'-end processing
Biological Process GO:0006406 mRNA export from nucleus
Biological Process GO:0000398 mRNA splicing, via spliceosome
Biological Process GO:0098789 pre-mRNA cleavage required for polyadenylation
Biological Process GO:0006369 termination of RNA polymerase II transcription
Biological Process GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
molecular function GO:0003723 RNA binding
molecular function GO:1990837 sequence-specific double-stranded DNA binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005847 mRNA cleavage and polyadenylation specificity factor complex
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript
R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts
R-HSA-1643685 Disease
R-HSA-168255 Influenza Infection
R-HSA-168276 NS1 Mediated Effects on Host Pathways
R-HSA-168315 Inhibition of Host mRNA Processing and RNA Silencing
R-HSA-5663205 Infectious disease
R-HSA-6784531 tRNA processing in the nucleus
R-HSA-72163 mRNA Splicing - Major Pathway
R-HSA-72172 mRNA Splicing
R-HSA-72187 mRNA 3'-end processing
R-HSA-72202 Transport of Mature Transcript to Cytoplasm
R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA
R-HSA-72306 tRNA processing
R-HSA-73856 RNA Polymerase II Transcription Termination
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-75067 Processing of Capped Intronless Pre-mRNA
R-HSA-77595 Processing of Intronless Pre-mRNAs
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001956 BXGD000092 Alcohol Use Disorder Chemically-Induced Disorders; Mental Disorders
C0002962 BXGD000160 Angina Pectoris Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014457 BXGD000915 Eosinophilia Hemic and Lymphatic Diseases
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0018834 BXGD001238 Heartburn Pathological Conditions, Signs and Symptoms
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0023508 BXGD001675 White Blood Cell Count procedure
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0031212 BXGD002295 Personality Disorders Mental Disorders
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0079298 BXGD003073 Epidermolysis Bullosa Simplex Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0201983 BXGD004064 Dehydroepiandrosterone sulfate measurement (procedure)
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0391976 BXGD008022 Pain Disorder Mental Disorders
C0441683 BXGD008809 Hormone measurement
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306759 BXGD012374 Eosinophilic disorder Hemic and Lymphatic Diseases
C1833661 BXGD013935 PAROXYSMAL EXTREME PAIN DISORDER Pathological Conditions, Signs and Symptoms
C2062441 BXGD016897 Influenza A
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C2748361 BXGD017588 H5N1 influenza
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002722 Nitrate 62
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein