protein

Showing entry for Apoptosis-inducing factor 1, mitochondrial

General Target Information
BXGT Id	BXGT005399
Protein Name	Apoptosis-inducing factor 1, mitochondrial
Uniport Id	O95831
Gene	AIFM1
Gene Id	9131
Domain	AIF_C; Pyr_redox
Pfam	PF14721 PF07992
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
4. Cellular Processes	4.2 Cell growth and death	hsa04210	Apoptosis
4. Cellular Processes	4.2 Cell growth and death	hsa04217	Necroptosis

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process	GO:0006915	apoptotic process
Biological Process	GO:1904045	cellular response to aldosterone
Biological Process	GO:0071392	cellular response to estradiol stimulus
Biological Process	GO:0070301	cellular response to hydrogen peroxide
Biological Process	GO:0071732	cellular response to nitric oxide
Biological Process	GO:0090650	cellular response to oxygen-glucose deprivation
Biological Process	GO:0030261	chromosome condensation
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Biological Process	GO:0033108	mitochondrial respiratory chain complex assembly
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly
Biological Process	GO:0051402	neuron apoptotic process
Biological Process	GO:0030182	neuron differentiation
Biological Process	GO:0055114	oxidation-reduction process
Biological Process	GO:0043065	positive regulation of apoptotic process
Biological Process	GO:0043525	positive regulation of neuron apoptotic process
Biological Process	GO:0045041	protein import into mitochondrial intermembrane space
Biological Process	GO:1902510	regulation of apoptotic DNA fragmentation
Biological Process	GO:0002931	response to ischemia
Biological Process	GO:1902065	response to L-glutamate
Biological Process	GO:0009636	response to toxic substance
molecular function	GO:0003677	DNA binding
molecular function	GO:0071949	FAD binding
molecular function	GO:0016174	NAD(P)H oxidase (H(2)O(2)-forming activity
molecular function	GO:0016651	oxidoreductase activity, acting on NAD(P)H
molecular function	GO:0046983	protein dimerization activity
cellular component	GO:0005829	cytosol
cellular component	GO:0005743	mitochondrial inner membrane
cellular component	GO:0005758	mitochondrial intermembrane space
cellular component	GO:0005739	mitochondrion
cellular component	GO:0005634	nucleus
cellular component	GO:0048471	perinuclear region of cytoplasm

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0002152	BXGD000104	Alloxan Diabetes	Nutritional and Metabolic Diseases; Endocrine System Diseases
C0003467	BXGD000194	Anxiety	Behavior and Behavior Mechanisms
C0003469	BXGD000195	Anxiety Disorders	Mental Disorders
C0004096	BXGD000252	Asthma	Respiratory Tract Diseases; Immune System Diseases
C0004114	BXGD000255	Astrocytoma	Neoplasms
C0004134	BXGD000256	Ataxia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0006142	BXGD000374	Malignant neoplasm of breast	Neoplasms; Skin and Connective Tissue Diseases
C0007758	BXGD000475	Cerebellar Ataxia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0007786	BXGD000486	Brain Ischemia	Nervous System Diseases; Cardiovascular Diseases
C0007787	BXGD000487	Transient Ischemic Attack	Nervous System Diseases; Cardiovascular Diseases
C0007847	BXGD000492	Malignant tumor of cervix	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007959	BXGD000507	Charcot-Marie-Tooth Disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0009375	BXGD000602	Colonic Neoplasms	Digestive System Diseases; Neoplasms
C0009402	BXGD000605	Colorectal Carcinoma	Digestive System Diseases; Neoplasms
C0011853	BXGD000752	Diabetes Mellitus, Experimental	Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854	BXGD000753	Diabetes Mellitus, Insulin-Dependent	Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011881	BXGD000760	Diabetic Nephropathy	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0014544	BXGD000926	Epilepsy	Nervous System Diseases
C0015644	BXGD001008	Muscular fasciculation	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0015934	BXGD001026	Fetal Growth Retardation	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0016202	BXGD001050	Flatfoot	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0017636	BXGD001131	Glioblastoma	Neoplasms
C0017638	BXGD001132	Glioma	Neoplasms
C0018784	BXGD001220	Sensorineural Hearing Loss (disorder)	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0019193	BXGD001299	Hepatitis, Toxic	Digestive System Diseases; Chemically-Induced Disorders
C0020179	BXGD001363	Huntington Disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0022107	BXGD001530	Irritable Mood	Behavior and Behavior Mechanisms
C0022821	BXGD001590	Kyphosis deformity of spine	Musculoskeletal Diseases
C0023467	BXGD001658	Leukemia, Myelocytic, Acute	Neoplasms
C0023520	BXGD001678	Leukodystrophy	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0023903	BXGD001720	Liver neoplasms	Digestive System Diseases; Neoplasms
C0024121	BXGD001735	Lung Neoplasms	Neoplasms; Respiratory Tract Diseases
C0025202	BXGD001832	melanoma	Neoplasms
C0025362	BXGD001866	Mental Retardation	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026848	BXGD001941	Myopathy	Musculoskeletal Diseases; Nervous System Diseases
C0027055	BXGD001964	Myocardial Reperfusion Injury	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027540	BXGD001996	Necrosis	Pathological Conditions, Signs and Symptoms
C0027627	BXGD002006	Neoplasm Metastasis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651	BXGD002009	Neoplasms	Neoplasms
C0027888	BXGD002056	Hereditary Motor and Sensory Neuropathies	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0029131	BXGD002116	Abnormality of the optic nerve
C0030567	BXGD002240	Parkinson Disease	Nervous System Diseases
C0031117	BXGD002285	Peripheral Neuropathy	Nervous System Diseases
C0033578	BXGD002408	Prostatic Neoplasms	Neoplasms; Male Urogenital Diseases
C0034372	BXGD002480	Quadriplegia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0034935	BXGD002497	Babinski Reflex
C0035229	BXGD002516	Respiratory Insufficiency	Respiratory Tract Diseases
C0035305	BXGD002529	Retinal Detachment	Eye Diseases
C0035334	BXGD002539	Retinitis Pigmentosa	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0036439	BXGD002615	Scoliosis, unspecified	Musculoskeletal Diseases
C0036572	BXGD002625	Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037317	BXGD002689	Sleep disturbances	Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0037772	BXGD002703	Spastic Paraplegia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038433	BXGD002754	Streptozotocin Diabetes	Nutritional and Metabolic Diseases; Endocrine System Diseases
C0038454	BXGD002760	Cerebrovascular accident	Nervous System Diseases; Cardiovascular Diseases
C0039273	BXGD002806	Talipes cavus	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0040264	BXGD002857	Tinnitus	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0040822	BXGD002885	Tremor	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0085084	BXGD003121	Motor Neuron Disease	Nervous System Diseases
C0085584	BXGD003195	Encephalopathies	Nervous System Diseases
C0086439	BXGD003284	Hypokinesia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0151313	BXGD003413	Sensory neuropathy	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0151786	BXGD003475	Muscle Weakness	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0151888	BXGD003497	Hyporeflexia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0151889	BXGD003498	Hyperreflexia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0152025	BXGD003521	Polyneuropathy	Nervous System Diseases
C0162666	BXGD003967	Mitochondrial Encephalomyopathies	Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0175693	BXGD004001	Russell-Silver syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0175754	BXGD004015	Agenesis of corpus callosum	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0205734	BXGD004115	Diabetes, Autoimmune	Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0206726	BXGD004271	gliosarcoma	Neoplasms
C0206743	BXGD004285	Rhabdoid Tumor	Neoplasms
C0220701	BXGD004325	RETINITIS PIGMENTOSA 1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0221032	BXGD004374	Familial generalized lipodystrophy	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0231686	BXGD004508	Gait, Unsteady	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234146	BXGD004626	Absent reflex	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235025	BXGD004713	Peripheral motor neuropathy	Nervous System Diseases
C0235946	BXGD004789	Cerebral atrophy	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0239548	BXGD004984	Fasciculation, Tongue	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0241005	BXGD005072	Creatine phosphokinase serum increased
C0242225	BXGD005143	Color blindness	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0242379	BXGD005157	Malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C0265290	BXGD005503	Metaphyseal chondrodysplasia	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0270612	BXGD006081	Leukoencephalopathy	Nervous System Diseases
C0270914	BXGD006131	Hereditary Motor and Sensory-Neuropathy Type II	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0270921	BXGD006133	Axonal neuropathy	Nervous System Diseases
C0271385	BXGD006193	Horizontal Nystagmus	Eye Diseases; Nervous System Diseases
C0278878	BXGD006609	Adult Glioblastoma	Neoplasms
C0279626	BXGD006657	Squamous cell carcinoma of esophagus	Digestive System Diseases; Neoplasms
C0280474	BXGD006748	Childhood Glioblastoma	Neoplasms
C0302592	BXGD006851	Cervix carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0338106	BXGD007167	Adenocarcinoma of colon	Digestive System Diseases; Neoplasms
C0338656	BXGD007211	Impaired cognition	Mental Disorders
C0339546	BXGD007268	Retinal Pigment Epithelial Detachment	Eye Diseases
C0342302	BXGD007458	Brittle diabetes	Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0344482	BXGD007678	Hypoplasia of corpus callosum	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0393525	BXGD008081	Progressive cerebellar ataxia	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0393541	BXGD008084	Distal Spinal Muscular Atrophy	Nervous System Diseases
C0393574	BXGD008095	Huntington Disease, Late Onset	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0393907	BXGD008154	Axonal sensorimotor neuropathy
C0424230	BXGD008522	Motor retardation	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0427065	BXGD008604	Distal muscle weakness	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0427144	BXGD008607	Toe-walking gait
C0432211	BXGD008737	Spondyloepimetaphyseal disorder	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0442874	BXGD008814	Neuropathy	Nervous System Diseases
C0454644	BXGD008850	Delayed speech and language development	Behavior and Behavior Mechanisms
C0476273	BXGD008986	Respiratory distress	Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0524851	BXGD009246	Neurodegenerative Disorders	Nervous System Diseases
C0541794	BXGD009262	Skeletal muscle atrophy
C0555198	BXGD009432	Malignant Glioma	Neoplasms
C0557874	BXGD009444	Global developmental delay
C0575081	BXGD009512	Gait abnormality	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0678222	BXGD009749	Breast Carcinoma	Neoplasms; Skin and Connective Tissue Diseases
C0684249	BXGD009790	Carcinoma of lung	Neoplasms; Respiratory Tract Diseases
C0699790	BXGD009866	Colon Carcinoma	Digestive System Diseases; Neoplasms
C0700201	BXGD009880	Dyssomnias	Nervous System Diseases; Mental Disorders
C0740391	BXGD009987	Middle Cerebral Artery Occlusion	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0740392	BXGD009988	Infarction, Middle Cerebral Artery	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0746674	BXGD010147	Generalized muscle weakness	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0751207	BXGD010348	Akinetic-Rigid Variant of Huntington Disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0751208	BXGD010349	Juvenile Huntington Disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0751651	BXGD010539	Mitochondrial Diseases	Nutritional and Metabolic Diseases
C0752308	BXGD010715	Hypoxia-Ischemia, Brain	Nervous System Diseases; Cardiovascular Diseases
C0795910	BXGD010763	COWCHOCK SYNDROME	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Otorhinolaryngologic Diseases
C0851578	BXGD010925	Sleep Disorders	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0860207	BXGD011220	Drug-Induced Liver Disease	Digestive System Diseases; Chemically-Induced Disorders
C0872084	BXGD011319	Sarcopenia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0949856	BXGD011588	Oxidative Phosphorylation Deficiencies	Nutritional and Metabolic Diseases
C1112256	BXGD011655	Sensorimotor neuropathy
C1167918	BXGD011779	Increased CSF lactate
C1262037	BXGD011865	Diabetic cystopathy
C1262760	BXGD011886	Hepatitis, Drug-Induced	Digestive System Diseases; Chemically-Induced Disorders
C1306460	BXGD012362	Primary malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C1384666	BXGD012948	hearing impairment	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1510586	BXGD013176	Autism Spectrum Disorders	Mental Disorders
C1519670	BXGD013241	Tumor Angiogenesis	Pathological Conditions, Signs and Symptoms
C1541317	BXGD013351	Adult Gliosarcoma	Neoplasms
C1565489	BXGD013401	Renal Insufficiency	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1611743	BXGD013456	Familial (FPAH)
C1621958	BXGD013468	Glioblastoma Multiforme	Neoplasms
C1833308	BXGD013910	NEURONOPATHY, DISTAL HEREDITARY MOTOR, TYPE V	Nervous System Diseases
C1836440	BXGD014115	Increased serum lactate	Nutritional and Metabolic Diseases
C1836542	BXGD014129	Depressed nasal bridge
C1836752	BXGD014158	Abnormal speech discrimination
C1836830	BXGD014165	Developmental regression	Mental Disorders
C1837522	BXGD014244	Impaired pain sensation
C1838180	BXGD014300	CODAS syndrome	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases; Stomatognathic Diseases
C1838663	BXGD014335	Enlargement of the wrists
C1838979	BXGD014349	MITOCHONDRIAL COMPLEX I DEFICIENCY	Nutritional and Metabolic Diseases
C1839630	BXGD014391	Severe muscular hypotonia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1840077	BXGD014434	Anteverted nostril
C1842364	BXGD014511	Central hypotonia
C1842587	BXGD014526	Sensory axonal neuropathy
C1843700	BXGD014604	Increased variability in muscle fiber diameter
C1845095	BXGD014709	DEAFNESS, X-LINKED 5 (disorder)	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Otorhinolaryngologic Diseases
C1845977	BXGD014769	X- linked recessive
C1846647	BXGD014833	DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1847584	BXGD014876	Distal sensory impairment	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1849488	BXGD015058	Increased serum pyruvate
C1852271	BXGD015268	Auditory neuropathy	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1852373	BXGD015276	Mitochondrial encephalopathy	Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C1853242	BXGD015322	Midface retrusion
C1854494	BXGD015409	Slow progression
C1857640	BXGD015726	Decreased nerve conduction velocity
C1858120	BXGD015774	Generalized hypotonia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1865384	BXGD016324	Amyotrophy, monomelic	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1866021	BXGD016363	Increased connective tissue
C1866141	BXGD016379	Foot dorsiflexor weakness
C1970840	BXGD016846	Leukoencephalopathy With Metaphyseal Chondrodysplasia	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C1970887	BXGD016851	Abnormal middle ear reflexes
C2237142	BXGD016960	Moderate global developmental delay
C2239176	BXGD016965	Liver carcinoma	Digestive System Diseases; Neoplasms
C2674432	BXGD017246	Reduced bone mineral density
C2674608	BXGD017250	Feeding difficulties in infancy
C2700617	BXGD017474	Irritation - emotion	Behavior and Behavior Mechanisms
C2732267	BXGD017551	Auditory neuropathy spectrum disorder	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C2749625	BXGD017629	Motor axonal neuropathy
C2931276	BXGD017994	Spastic paraplegia 17	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C3151753	BXGD018449	COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 6
C3275417	BXGD018663	Ragged-red muscle fibers
C3658290	BXGD019256	Drug-Induced Acute Liver Injury	Digestive System Diseases; Chemically-Induced Disorders
C3665347	BXGD019279	Visual Impairment	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3714756	BXGD019429	Intellectual Disability	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3806467	BXGD019513	Respiratory insufficiency due to muscle weakness	Respiratory Tract Diseases
C3837958	BXGD019756	Diabetes Mellitus, Ketosis-Prone	Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C3899658	BXGD020092	Childhood Gliosarcoma	Neoplasms
C4021761	BXGD020763	Morphological abnormality of the pyramidal tract
C4021991	BXGD020861	Abnormality of the astrocytes
C4022749	BXGD020980	Abnormal brainstem MRI signal intensity
C4023607	BXGD021226	Abnormal corpus striatum morphology
C4048328	BXGD021903	cervical cancer	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4225180	BXGD022169	EVEN-PLUS SYNDROME
C4274109	BXGD022346	Autosomal dominant Charcot-Marie-Tooth disease type 2D	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4277682	BXGD022376	Chemical and Drug Induced Liver Injury	Digestive System Diseases; Chemically-Induced Disorders
C4279912	BXGD022378	Chemically-Induced Liver Toxicity	Digestive System Diseases; Chemically-Induced Disorders
C4280736	BXGD022394	Large knee
C4304400	BXGD022574	X-linked hereditary sensory and autonomic neuropathy with deafness	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4520981	BXGD023051	Abnormality of the basal ganglia
C4551551	BXGD023345	X-linked hereditary motor and sensory neuropathy	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4551915	BXGD023441	Gait Disturbance, CTCAE
C4552810	BXGD023525	Irritability, CTCAE
C4552811	BXGD023526	Generalized Muscle Weakness, CTCAE
C4554117	BXGD023561	Diabetes Mellitus, Sudden-Onset	Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C4721453	BXGD023744	Peripheral Nervous System Diseases	Nervous System Diseases
C4722085	BXGD023788	Malignant neoplasm of colon and/or rectum

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000436	Glycerol		92.09

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}