Showing entry for Diphosphoinositol polyphosphate phosphohydrolase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005411
Protein NameDiphosphoinositol polyphosphate phosphohydrolase 1
Uniport IdO95989
GeneNUDT3
Gene Id11165
DomainNUDIX
Pfam PF00293  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1901911 adenosine 5'-(hexahydrogen pentaphosphate) catabolic process
Biological Process GO:0007267 cell-cell signaling
Biological Process GO:1901909 diadenosine hexaphosphate catabolic process
Biological Process GO:1901907 diadenosine pentaphosphate catabolic process
Biological Process GO:0015961 diadenosine polyphosphate catabolic process
Biological Process GO:0071544 diphosphoinositol polyphosphate catabolic process
Biological Process GO:0071543 diphosphoinositol polyphosphate metabolic process
Biological Process GO:0043647 inositol phosphate metabolic process
molecular function GO:0034431 bis(5'-adenosyl)-hexaphosphatase activity
molecular function GO:0034432 bis(5'-adenosyl)-pentaphosphatase activity
molecular function GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity
molecular function GO:0000298 endopolyphosphatase activity
molecular function GO:0052842 inositol diphosphate pentakisphosphate diphosphatase activity
molecular function GO:0052840 inositol diphosphate tetrakisphosphate diphosphatase activity
molecular function GO:0050072 m7G(5')pppN diphosphatase activity
molecular function GO:0000287 magnesium ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1483249 Inositol phosphate metabolism
R-HSA-1855167 Synthesis of pyrophosphates in the cytosol
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005890 BXGD000345 Body Height
C0005893 BXGD000346 Body mass index procedure
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0424101 BXGD008519 Inattention
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0578022 BXGD009541 Finding of body mass index
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1305855 BXGD012348 Body mass index
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000140 Phytic acid 660.04
BXGC0002588 Magnesium 24.31
BXGC0002698 Fluorine 19
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein