Showing entry for Phospholipase A2, major isoenzyme



                       
General Target Information
BXGT IdBXGT005593
Protein NamePhospholipase A2, major isoenzyme
Uniport IdP00592
GenePLA2G1B
Gene Id445525
DomainPhospholip_A2_1
Pfam PF00068  
OrganismSus scrofa (Pig)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0032869 cellular response to insulin stimulus
Biological Process GO:0006633 fatty acid biosynthetic process
Biological Process GO:0032637 interleukin-8 production
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0019370 leukotriene biosynthetic process
Biological Process GO:0016042 lipid catabolic process
Biological Process GO:0030593 neutrophil chemotaxis
Biological Process GO:0002446 neutrophil mediated immunity
Biological Process GO:0046470 phosphatidylcholine metabolic process
Biological Process GO:0046471 phosphatidylglycerol metabolic process
Biological Process GO:0010524 positive regulation of calcium ion transport into cytosol
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0048146 positive regulation of fibroblast proliferation
Biological Process GO:1904635 positive regulation of glomerular visceral epithelial cell apoptotic process
Biological Process GO:0050778 positive regulation of immune response
Biological Process GO:0051092 positive regulation of NF-kappaB transcription factor activity
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0046324 regulation of glucose import
molecular function GO:0032052 bile acid binding
molecular function GO:0047498 calcium-dependent phospholipase A2 activity
molecular function GO:0005509 calcium ion binding
molecular function GO:0004623 phospholipase A2 activity
molecular function GO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
molecular function GO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
molecular function GO:0005102 signaling receptor binding
cellular component GO:0009986 cell surface
cellular component GO:0005576 extracellular region
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001002 1,2-Benzenediol 110.11
BXGC0002586 Calcium 40.08
BXGC0003627 alpha-Linoleic acid 280.45
BXGC0003705 Chloride 35.45
BXGC0004714 2-Methoxy-1,4-benzoquinone 138.12
BXGC0005254 Dibutyl phthalate 278.34
BXGC0005513 Hexadecanoic acid 256.42
BXGC0022447 2-Naphthalen-1-Ylacetic Acid 186.07
BXGC0038899 Erucic Acid 338.32
BXGC0044334 P-Nitrophenol 139.03
BXGC0047281 Berberine 336.12
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein