protein

Showing entry for Immunoglobulin heavy constant epsilon

　　　　　　　　　　　　

General Target Information
BXGT Id	BXGT005795
Protein Name	Immunoglobulin heavy constant epsilon
Uniport Id	P01854
Gene	IGHE
Gene Id
Domain	C1-set
Pfam	PF07654
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0050853	B cell receptor signaling pathway
Biological Process	GO:0006958	complement activation, classical pathway
Biological Process	GO:0019221	cytokine-mediated signaling pathway
Biological Process	GO:0042742	defense response to bacterium
Biological Process	GO:0038095	Fc-epsilon receptor signaling pathway
Biological Process	GO:0006955	immune response
Biological Process	GO:0045087	innate immune response
Biological Process	GO:0006911	phagocytosis, engulfment
Biological Process	GO:0006910	phagocytosis, recognition
Biological Process	GO:0050871	positive regulation of B cell activation
molecular function	GO:0003823	antigen binding
molecular function	GO:0034987	immunoglobulin receptor binding
cellular component	GO:0009897	external side of plasma membrane
cellular component	GO:0005576	extracellular region
cellular component	GO:0042571	immunoglobulin complex, circulating

Reactome

Pathway Id	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system
R-HSA-168249	Innate Immune System
R-HSA-168249	Innate Immune System
R-HSA-168256	Immune System
R-HSA-168256	Immune System
R-HSA-2454202	Fc epsilon receptor (FCERI) signaling
R-HSA-2454202	Fc epsilon receptor (FCERI) signaling
R-HSA-2730905	Role of LAT2/NTAL/LAB on calcium mobilization
R-HSA-2730905	Role of LAT2/NTAL/LAB on calcium mobilization
R-HSA-2871796	FCERI mediated MAPK activation
R-HSA-2871809	FCERI mediated Ca+2 mobilization
R-HSA-2871809	FCERI mediated Ca+2 mobilization
R-HSA-2871837	FCERI mediated NF-kB activation
R-HSA-449147	Signaling by Interleukins
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000436	Glycerol		92.09
BXGC0018397	beta-1,4-mannan		180.06
BXGC0030612	tetraethylene glycol		194.12
BXGC0031626	carbitol		134.09
BXGC0050194	alpha-D-Mannose		180.06

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}