Showing entry for Immunoglobulin heavy constant gamma 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005796
Protein NameImmunoglobulin heavy constant gamma 1
Uniport IdP01857
GeneIGHG1
Gene Id
DomainC1-set
Pfam PF07654  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0050853 B cell receptor signaling pathway
Biological Process GO:0006956 complement activation
Biological Process GO:0006958 complement activation, classical pathway
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0042742 defense response to bacterium
Biological Process GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
Biological Process GO:0045087 innate immune response
Biological Process GO:0006911 phagocytosis, engulfment
Biological Process GO:0006910 phagocytosis, recognition
Biological Process GO:0050871 positive regulation of B cell activation
Biological Process GO:0030449 regulation of complement activation
molecular function GO:0003823 antigen binding
molecular function GO:0034987 immunoglobulin receptor binding
cellular component GO:0072562 blood microparticle
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0042571 immunoglobulin complex, circulating
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1643685 Disease
R-HSA-1643685 Disease
R-HSA-166658 Complement cascade
R-HSA-166663 Initial triggering of complement
R-HSA-166786 Creation of C4 and C2 activators
R-HSA-168249 Innate Immune System
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168256 Immune System
R-HSA-173623 Classical antibody-mediated complement activation
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029481 FCGR activation
R-HSA-2029481 FCGR activation
R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-HSA-2029485 Role of phospholipids in phagocytosis
R-HSA-449147 Signaling by Interleukins
R-HSA-5663205 Infectious disease
R-HSA-5663205 Infectious disease
R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling
R-HSA-9658195 Leishmania infection
R-HSA-9658195 Leishmania infection
R-HSA-9662851 Anti-inflammatory response favouring Leishmania parasite infection
R-HSA-9662851 Anti-inflammatory response favouring Leishmania parasite infection
R-HSA-9664323 FCGR3A-mediated IL10 synthesis
R-HSA-9664323 FCGR3A-mediated IL10 synthesis
R-HSA-9664407 Parasite infection
R-HSA-9664407 Parasite infection
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
R-HSA-9664433 Leishmania parasite growth and survival
R-HSA-9664433 Leishmania parasite growth and survival
R-HSA-977606 Regulation of Complement cascade
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002444 Methyl nonanoate 172.26
BXGC0002591 Potassium 39.1
BXGC0002616 Copper 63.55
BXGC0003705 Chloride 35.45
BXGC0003765 Psidiolic acid 129.11
BXGC0012706 4-hydroxy-5-nitrophenyl acetic acid 197.03
BXGC0018397 beta-1,4-mannan 180.06
BXGC0027956 SHU 508 180.06
BXGC0030612 tetraethylene glycol 194.12
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
BXGC0049447 acetate 59.01
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein