Showing entry for Segmentation polarity homeobox protein engrailed


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005972
Protein NameSegmentation polarity homeobox protein engrailed
Uniport IdP02836
Geneen
Gene Id36240
DomainEngrail_1_C_sig; Homeodomain
Pfam PF10525   PF00046  
OrganismDrosophila melanogaster (Fruit fly)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007487 analia development
Biological Process GO:0048099 anterior/posterior lineage restriction, imaginal disc
Biological Process GO:0035288 anterior head segmentation
Biological Process GO:0007411 axon guidance
Biological Process GO:0007386 compartment pattern specification
Biological Process GO:0035224 genital disc anterior/posterior pattern formation
Biological Process GO:0035215 genital disc development
Biological Process GO:0008406 gonad development
Biological Process GO:0007474 imaginal disc-derived wing vein specification
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0007400 neuroblast fate determination
Biological Process GO:0030182 neuron differentiation
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0007388 posterior compartment specification
Biological Process GO:0035289 posterior head segmentation
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0007367 segment polarity determination
Biological Process GO:0035277 spiracle morphogenesis, open tracheal system
Biological Process GO:0035290 trunk segmentation
Biological Process GO:0007418 ventral midline development
Biological Process GO:0048100 wing disc anterior/posterior pattern formation
Biological Process GO:0007472 wing disc morphogenesis
molecular function GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
cellular component GO:0005634 nucleus
cellular component GO:0016586 RSC-type complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein