Showing entry for Gag-Pol polyprotein



                       
General Target Information
BXGT IdBXGT006056
Protein NameGag-Pol polyprotein
Uniport IdP03366
Genegag-pol
Gene Id
DomainGag_p17; Gag_p24; Integrase_Zn; IN_DBD_C; RNase_H; rve; RVP; RVT_1; RVT_connect; RVT_thumb; zf-CCHC
Pfam PF00540   PF00607   PF00552   PF02022   PF00075   PF00665   PF00077   PF00078   PF06815   PF06817   PF00098  
OrganismHuman immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015074 DNA integration
Biological Process GO:0006310 DNA recombination
Biological Process GO:0075713 establishment of integrated proviral latency
Biological Process GO:0039651 induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0039657 suppression by virus of host gene expression
Biological Process GO:0046718 viral entry into host cell
Biological Process GO:0044826 viral genome integration into host DNA
Biological Process GO:0075732 viral penetration into host nucleus
molecular function GO:0004190 aspartic-type endopeptidase activity
molecular function GO:0003677 DNA binding
molecular function GO:0003887 DNA-directed DNA polymerase activity
molecular function GO:0004533 exoribonuclease H activity
molecular function GO:0008289 lipid binding
molecular function GO:0003723 RNA binding
molecular function GO:0003964 RNA-directed DNA polymerase activity
molecular function GO:0004523 RNA-DNA hybrid ribonuclease activity
molecular function GO:0005198 structural molecule activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0042025 host cell nucleus
cellular component GO:0020002 host cell plasma membrane
cellular component GO:0072494 host multivesicular body
cellular component GO:0019013 viral nucleocapsid
cellular component GO:0055036 virion membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0002675 Sugars 342.3
BXGC0003705 Chloride 35.45
BXGC0004277 Acetic acid 60.05
BXGC0005625 alpha-D-Glucopyranose 180.16
BXGC0006368 Formic acid 46.03
BXGC0028682 (2S)-1-Linoleoyl-2-Palmitoyl-3-O-Beta-D-Galactopyranosylglycerol 754.56
BXGC0045255 R 82913 321.11
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein