protein

General Target Information
BXGT Id	BXGT006064
Protein Name	Protein Nef
Uniport Id	P03404
Gene	nef
Gene Id
Domain	F-protein
Pfam	PF00469
Organism	Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0045225	negative regulation of CD4 production
Biological Process	GO:0009405	pathogenesis
Biological Process	GO:0050848	regulation of calcium-mediated signaling
Biological Process	GO:0052085	suppression by symbiont of host T-cell mediated immune response
Biological Process	GO:0039504	suppression by virus of host adaptive immune response
Biological Process	GO:0046776	suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I
Biological Process	GO:0039505	suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II
Biological Process	GO:0039521	suppression by virus of host autophagy
Biological Process	GO:0019058	viral life cycle
molecular function	GO:0051117	ATPase binding
molecular function	GO:0042609	CD4 receptor binding
molecular function	GO:0005525	GTP binding
molecular function	GO:0042288	MHC class I protein binding
molecular function	GO:0019901	protein kinase binding
molecular function	GO:0017124	SH3 domain binding
molecular function	GO:0005102	signaling receptor binding
molecular function	GO:0031996	thioesterase binding
cellular component	GO:0005576	extracellular region
cellular component	GO:0044178	host cell Golgi membrane
cellular component	GO:0020002	host cell plasma membrane
cellular component	GO:0016020	membrane
cellular component	GO:0019012	virion

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}