Showing entry for RNA-directed RNA polymerase catalytic subunit


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006069
Protein NameRNA-directed RNA polymerase catalytic subunit
Uniport IdP03431
GenePB1
Gene Id956534
DomainFlu_PB1
Pfam PF00602  
OrganismInfluenza A virus (strain A/Puerto Rico/8/1934 H1N1)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019064 fusion of virus membrane with host plasma membrane
Biological Process GO:0075733 intracellular transport of virus
Biological Process GO:0019065 receptor-mediated endocytosis of virus by host cell
Biological Process GO:0039523 suppression by virus of host RNA polymerase II activity
Biological Process GO:0006351 transcription, DNA-templated
Biological Process GO:0019061 uncoating of virus
Biological Process GO:0046761 viral budding from plasma membrane
Biological Process GO:0019070 viral genome maturation
Biological Process GO:0019072 viral genome packaging
Biological Process GO:0039694 viral RNA genome replication
Biological Process GO:0019083 viral transcription
Biological Process GO:0019062 virion attachment to host cell
molecular function GO:0000166 nucleotide binding
molecular function GO:0003723 RNA binding
molecular function GO:0003968 RNA-directed 5'-3' RNA polymerase activity
cellular component GO:0005829 cytosol
cellular component GO:0031904 endosome lumen
cellular component GO:0005576 extracellular region
cellular component GO:0030430 host cell cytoplasm
cellular component GO:0042025 host cell nucleus
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1643685 Disease
R-HSA-168255 Influenza Infection
R-HSA-168268 Virus Assembly and Release
R-HSA-168270 Fusion and Uncoating of the Influenza Virion
R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus
R-HSA-168273 Influenza Viral RNA Transcription and Replication
R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus
R-HSA-168275 Entry of Influenza Virion into Host Cell via Endocytosis
R-HSA-168288 Fusion of the Influenza Virion to the Host Cell Endosome
R-HSA-168298 Release
R-HSA-168302 Budding
R-HSA-168303 Packaging of Eight RNA Segments
R-HSA-168325 Viral Messenger RNA Synthesis
R-HSA-168330 Viral RNP Complexes in the Host Cell Nucleus
R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery
R-HSA-168336 Uncoating of the Influenza Virion
R-HSA-192814 vRNA Synthesis
R-HSA-192823 Viral mRNA Translation
R-HSA-192869 cRNA Synthesis
R-HSA-192905 vRNP Assembly
R-HSA-5663205 Infectious disease
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0044778 Oseltamivir 312.2
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein