Showing entry for Non-structural protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006086
Protein NameNon-structural protein 1
Uniport IdP03496
GeneNS
Gene Id956533
DomainFlu_NS1
Pfam PF00600  
OrganismInfluenza A virus (strain A/Puerto Rico/8/1934 H1N1)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030683 mitigation of host immune response by virus
Biological Process GO:0046778 modification by virus of host mRNA processing
Biological Process GO:0019054 modulation by virus of host cellular process
Biological Process GO:0039524 suppression by virus of host mRNA processing
Biological Process GO:0039580 suppression by virus of host PKR activity
Biological Process GO:0039540 suppression by virus of host RIG-I activity
Biological Process GO:0039502 suppression by virus of host type I interferon-mediated signaling pathway
molecular function GO:0042802 identical protein binding
molecular function GO:0003723 RNA binding
cellular component GO:0005829 cytosol
cellular component GO:0030430 host cell cytoplasm
cellular component GO:0042025 host cell nucleus
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1169408 ISG15 antiviral mechanism
R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1643685 Disease
R-HSA-168255 Influenza Infection
R-HSA-168256 Immune System
R-HSA-168273 Influenza Viral RNA Transcription and Replication
R-HSA-168276 NS1 Mediated Effects on Host Pathways
R-HSA-168305 Inhibition of Interferon Synthesis
R-HSA-168315 Inhibition of Host mRNA Processing and RNA Silencing
R-HSA-168888 Inhibition of IFN-beta
R-HSA-169131 Inhibition of PKR
R-HSA-192823 Viral mRNA Translation
R-HSA-5213460 RIPK1-mediated regulated necrosis
R-HSA-5218859 Regulated Necrosis
R-HSA-5357801 Programmed Cell Death
R-HSA-5663205 Infectious disease
R-HSA-913531 Interferon Signaling
R-HSA-9686347 Microbial modulation of RIPK1-mediated regulated necrosis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein