Showing entry for Sarcoplasmic/endoplasmic reticulum calcium ATPase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006170
Protein NameSarcoplasmic/endoplasmic reticulum calcium ATPase 1
Uniport IdP04191
GeneATP2A1
Gene Id100037716
DomainCation_ATPase; Cation_ATPase_C; Cation_ATPase_N; E1-E2_ATPase
Pfam PF00689   PF00690  
OrganismOryctolagus cuniculus (Rabbit)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1990036 calcium ion import into sarcoplasmic reticulum
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0045988 negative regulation of striated muscle contraction
Biological Process GO:1901896 positive regulation of ATPase-coupled calcium transmembrane transporter activity
Biological Process GO:1902082 positive regulation of calcium ion import into sarcoplasmic reticulum
Biological Process GO:0106134 positive regulation of cardiac muscle cell contraction
Biological Process GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction
Biological Process GO:0006942 regulation of striated muscle contraction
molecular function GO:0016887 ATPase activity
molecular function GO:0005524 ATP binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0005388 calcium transmembrane transporter activity, phosphorylative mechanism
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0031673 H zone
cellular component GO:0031674 I band
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0016529 sarcoplasmic reticulum
cellular component GO:0033017 sarcoplasmic reticulum membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0002591 Potassium 39.1
BXGC0003705 Chloride 35.45
BXGC0003757 2-Methylpropan-2-ol 74.12
BXGC0004275 Acetaldehyde 44.05
BXGC0034783 Doxorubicin 543.17
BXGC0036595 alisol B 472.36
BXGC0049447 acetate 59.01
BXGC0051271 maltose 342.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein