Showing entry for Protein Nef


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006188
Protein NameProtein Nef
Uniport IdP04324
Genenef
Gene Id
DomainF-protein
Pfam PF00469  
OrganismHuman immunodeficiency virus type 1 group M subtype B (isolate PCV12) (HIV-1)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0045225 negative regulation of CD4 production
Biological Process GO:0009405 pathogenesis
Biological Process GO:0050848 regulation of calcium-mediated signaling
Biological Process GO:0052085 suppression by symbiont of host T-cell mediated immune response
Biological Process GO:0039504 suppression by virus of host adaptive immune response
Biological Process GO:0046776 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I
Biological Process GO:0039505 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II
Biological Process GO:0039521 suppression by virus of host autophagy
Biological Process GO:0019058 viral life cycle
molecular function GO:0051117 ATPase binding
molecular function GO:0042609 CD4 receptor binding
molecular function GO:0005525 GTP binding
molecular function GO:0042288 MHC class I protein binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0017124 SH3 domain binding
molecular function GO:0005102 signaling receptor binding
molecular function GO:0031996 thioesterase binding
cellular component GO:0005576 extracellular region
cellular component GO:0044178 host cell Golgi membrane
cellular component GO:0020002 host cell plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0019012 virion
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002144 Tetradecanoic acid 228.37
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein