Showing entry for Protein kinase C alpha type


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006379
Protein NameProtein kinase C alpha type
Uniport IdP05696
GenePrkca
Gene Id
DomainC1_1; C2; Pkinase; Pkinase_C
Pfam PF00130   PF00168   PF00069   PF00433  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0001525 angiogenesis
Biological Process GO:0007155 cell adhesion
Biological Process GO:0006874 cellular calcium ion homeostasis
Biological Process GO:0071322 cellular response to carbohydrate stimulus
Biological Process GO:0021955 central nervous system neuron axonogenesis
Biological Process GO:0002062 chondrocyte differentiation
Biological Process GO:0002159 desmosome assembly
Biological Process GO:0045184 establishment of protein localization
Biological Process GO:0035408 histone H3-T6 phosphorylation
Biological Process GO:0000188 inactivation of MAPK activity
Biological Process GO:0050930 induction of positive chemotaxis
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0097193 intrinsic apoptotic signaling pathway
Biological Process GO:0007611 learning or memory
Biological Process GO:0010360 negative regulation of anion channel activity
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0034351 negative regulation of glial cell apoptotic process
Biological Process GO:0046325 negative regulation of glucose import
Biological Process GO:0045822 negative regulation of heart contraction
Biological Process GO:0046627 negative regulation of insulin receptor signaling pathway
Biological Process GO:0006469 negative regulation of protein kinase activity
Biological Process GO:0001933 negative regulation of protein phosphorylation
Biological Process GO:0017148 negative regulation of translation
Biological Process GO:0030593 neutrophil chemotaxis
Biological Process GO:0036289 peptidyl-serine autophosphorylation
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0018107 peptidyl-threonine phosphorylation
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:0043536 positive regulation of blood vessel endothelial cell migration
Biological Process GO:0045780 positive regulation of bone resorption
Biological Process GO:0010613 positive regulation of cardiac muscle hypertrophy
Biological Process GO:0045785 positive regulation of cell adhesion
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:2000707 positive regulation of dense core granule biogenesis
Biological Process GO:0010595 positive regulation of endothelial cell migration
Biological Process GO:0001938 positive regulation of endothelial cell proliferation
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0045921 positive regulation of exocytosis
Biological Process GO:0050729 positive regulation of inflammatory response
Biological Process GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway
Biological Process GO:0045651 positive regulation of macrophage differentiation
Biological Process GO:0045931 positive regulation of mitotic cell cycle
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0048661 positive regulation of smooth muscle cell proliferation
Biological Process GO:0051965 positive regulation of synapse assembly
Biological Process GO:0099171 presynaptic modulation of chemical synaptic transmission
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0006937 regulation of muscle contraction
Biological Process GO:0050730 regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:0090330 regulation of platelet aggregation
Biological Process GO:0048259 regulation of receptor-mediated endocytosis
Biological Process GO:0047484 regulation of response to osmotic stress
Biological Process GO:2000300 regulation of synaptic vesicle exocytosis
Biological Process GO:0002026 regulation of the force of heart contraction
Biological Process GO:0046677 response to antibiotic
Biological Process GO:0051412 response to corticosterone
Biological Process GO:0032355 response to estradiol
Biological Process GO:0045471 response to ethanol
Biological Process GO:0070555 response to interleukin-1
Biological Process GO:0009612 response to mechanical stimulus
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0043434 response to peptide hormone
Biological Process GO:0000302 response to reactive oxygen species
Biological Process GO:0009636 response to toxic substance
molecular function GO:0005524 ATP binding
molecular function GO:0004698 calcium-dependent protein kinase C activity
molecular function GO:0019899 enzyme binding
molecular function GO:0035403 histone kinase activity (H3-T6 specific)
molecular function GO:0005178 integrin binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0004697 protein kinase C activity
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0035866 alphav-beta3 integrin-PKCalpha complex
cellular component GO:0045177 apical part of cell
cellular component GO:0030424 axon
cellular component GO:0044305 calyx of Held
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0014704 intercalated disc
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0031966 mitochondrial membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0001750 photoreceptor outer segment
cellular component GO:0005886 plasma membrane
cellular component GO:0099523 presynaptic cytosol
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000130 Estradiol 272.38
BXGC0000759 Arabinan 243.22
BXGC0001765 (E)-Resveratrol 3-glucoside 390.39
BXGC0001767 (E)-Resveratrol 228.25
BXGC0002579 (Z)-Resveratrol 3-glucoside 390.38
BXGC0002586 Calcium 40.08
BXGC0002702 Lead 207.2
BXGC0002961 Thiophen-3-carboxyaldehyde 112.15
BXGC0003364 Cerebroside 299.49
BXGC0003772 Corilagin 634.45
BXGC0004275 Acetaldehyde 44.05
BXGC0006057 (Z)-Resveratrol 228.25
BXGC0007052 Olomoucine 298.34
BXGC0012352 Chelerythrine 348.12
BXGC0021390 n.a 390.13
BXGC0025876 Acetoside 624.21
BXGC0034756 3,5,4'-trihydroxystilbene-4'-O-glucoside 390.13
BXGC0044194 Punicafolin 938.1
BXGC0045812 Trifluoperazine 407.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein