Showing entry for Glucocorticoid receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006452
Protein NameGlucocorticoid receptor
Uniport IdP06537
GeneNr3c1
Gene Id
DomainGCR; Hormone_recep; zf-C4
Pfam PF02155   PF00104   PF00105  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030325 adrenal gland development
Biological Process GO:0071549 cellular response to dexamethasone stimulus
Biological Process GO:0071385 cellular response to glucocorticoid stimulus
Biological Process GO:0071383 cellular response to steroid hormone stimulus
Biological Process GO:0071560 cellular response to transforming growth factor beta stimulus
Biological Process GO:0048096 chromatin-mediated maintenance of transcription
Biological Process GO:0006338 chromatin remodeling
Biological Process GO:0008211 glucocorticoid metabolic process
Biological Process GO:0042921 glucocorticoid receptor signaling pathway
Biological Process GO:0060603 mammary gland duct morphogenesis
Biological Process GO:0042711 maternal behavior
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:1900170 negative regulation of glucocorticoid mediated signaling pathway
Biological Process GO:0031914 negative regulation of synaptic plasticity
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0043116 negative regulation of vascular permeability
Biological Process GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development
Biological Process GO:0060999 positive regulation of dendritic spine development
Biological Process GO:2000324 positive regulation of glucocorticoid receptor signaling pathway
Biological Process GO:0014049 positive regulation of glutamate secretion
Biological Process GO:0043525 positive regulation of neuron apoptotic process
Biological Process GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0031946 regulation of glucocorticoid biosynthetic process
Biological Process GO:0006111 regulation of gluconeogenesis
Biological Process GO:0010906 regulation of glucose metabolic process
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0046685 response to arsenic-containing substance
molecular function GO:0003682 chromatin binding
molecular function GO:0001046 core promoter sequence-specific DNA binding
molecular function GO:0003677 DNA binding
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
molecular function GO:0003690 double-stranded DNA binding
molecular function GO:0004883 glucocorticoid receptor activity
molecular function GO:0031072 heat shock protein binding
molecular function GO:0042562 hormone binding
molecular function GO:0030544 Hsp70 protein binding
molecular function GO:0051879 Hsp90 protein binding
molecular function GO:0042802 identical protein binding
molecular function GO:0004879 nuclear receptor activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0030971 receptor tyrosine kinase binding
molecular function GO:0070491 repressing transcription factor binding
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:1990837 sequence-specific double-stranded DNA binding
molecular function GO:0005496 steroid binding
molecular function GO:1990239 steroid hormone binding
molecular function GO:0003713 transcription coactivator activity
molecular function GO:0008134 transcription factor binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0043197 dendritic spine
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0016020 membrane
cellular component GO:0005815 microtubule organizing center
cellular component GO:0005739 mitochondrion
cellular component GO:0043005 neuron projection
cellular component GO:0016607 nuclear speck
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0014069 postsynaptic density
cellular component GO:0099092 postsynaptic density, intracellular component
cellular component GO:0032991 protein-containing complex
cellular component GO:0005819 spindle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0024141 Hydrocortisone 362.21
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein